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Clinical Trial Summary

Aim of this trial is to define if Post-Operative Cognitive Dysfunction, detected analyzing changes between pre-operative and post-operative Neurocognitive Test, relate to concentration of effector's site concentration of propofol and remifentanil TCI and to the common intraoperative neuromonitoring values.


Clinical Trial Description

Post-Operative Cognitive Dysfunction has not been yet investigated after general anaesthesia with Targeted-Controlled-Infusion (TCI) and Laryngeal-Mask-Airway (LMA), daily used in the investigator's Hospital to anesthetize women undergoing breast surgery. Aim of this trial is to define if neurocognitive tests (Montreal Cognitive Assessment, Trail Making Test A and B, Digit Span Test) before and after surgery relate to concentrations at effector's site (Ec) of propofol and remifentanil TCI and the values of Bispectral Index and Entropy monitoring and Surgical Plethysmographic Index (SPI). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03774420
Study type Observational
Source University of Padova
Contact Federico Linassi, MD
Phone 049 8754256
Email federico.linassi@studenti.unipd.it
Status Recruiting
Phase
Start date July 3, 2019
Completion date December 31, 2024

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