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Emergence Delirium clinical trials

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NCT ID: NCT04092894 Recruiting - Insomnia Clinical Trials

Suvorexant and Sleep/Delirium in ICU Patients

Start date: February 28, 2020
Phase: Phase 4
Study type: Interventional

Investigators will evaluate the efficacy of postoperative oral suvorexant treatment on nighttime wakefulness after persistent sleep onset (WASO) among adult cardiac surgical patients recovering in the cardiac intensive care unit (ICU). The study include patients ≥ 60 years old undergoing coronary artery bypass graft surgery (CABG), with or without valve surgery (aortic or mitral). Patients will receive either oral suvorexant or placebo for 7 nights starting the night after extubation. The primary hypothesis is that suvorexant compared with placebo decreases WASO, as measured by a specialized electroencephalogram (EEG), the SedLine monitor, during the first night in the cardiac ICU. Investigators will also assess total sleep time (TST), time to sleep onset (TSO), and postoperative delirium and delirium-free days.

NCT ID: NCT04091724 Recruiting - Delirium Clinical Trials

Perioperative EEG-Monitoring and Emergence Delirium in Children

Start date: December 2, 2019
Phase:
Study type: Observational

Emergence delirium is a significant problem, particularly in children. However the incidence, preventative strategies, and management of emergence delirium remain unclear. Multichannel electroencephalogram is a recognized tool for identifying neurophysiologic states during anesthesia, sleep, and arousal. The aim of the current study is to evaluate the mechanisms and predictors of emergence delirium in children under 16 years scheduled for elective surgery using electroencephalogram. The "Pediatric Anesthesia Emergence Delirium Scores (PAED Score)" (Sikich et al. 2004) is used to screen for the occurrence of emergence delirium in the post anesthesia care unit.

NCT ID: NCT04043663 Recruiting - Emergence Delirium Clinical Trials

Effects of Virtual Reality on Perioperative Pediatric Anxiety

VIRTUALPED
Start date: July 15, 2019
Phase: N/A
Study type: Interventional

This study evaluates the effect of virtual reality on anxiety levels in a pediatric surgical population. Half of participants will receive standard perioperative treatment, while the other half will receive additionally a virtual reality local program.

NCT ID: NCT04027751 Recruiting - Clinical trials for Postoperative Delirium

The Efficacy and Safety of Tropisetron in Preventing Emergence Delirium

Start date: August 1, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the efficacy and safety of Tropisetron in preventing emergence delirium.

NCT ID: NCT03839784 Recruiting - Clinical trials for Cognitive Impairment

Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient

Start date: September 1, 2020
Phase:
Study type: Observational [Patient Registry]

The research team is creating a foundational infrastructure in order to develop a precision medicine approach for geriatric patients who require surgery with anesthesia. The team plans to build the first of its kind comprehensive database of demographic and risk factor questionnaire responses, biobanked blood specimens, intraoperative electroencephalography (EEG), and inclusive cognitive testing throughout patient interaction starting at the preop appointment until a year later. This will be used to create a predictive model of periooperative neurocognitive disorders.

NCT ID: NCT03774420 Recruiting - Emergence Delirium Clinical Trials

Post Operative Cognitive Dysfunction After Breast Surgery

Start date: July 3, 2019
Phase:
Study type: Observational

Aim of this trial is to define if Post-Operative Cognitive Dysfunction, detected analyzing changes between pre-operative and post-operative Neurocognitive Test, relate to concentration of effector's site concentration of propofol and remifentanil TCI and to the common intraoperative neuromonitoring values.

NCT ID: NCT03398759 Recruiting - Agitation Clinical Trials

Butorphanol Mitigate Emergence Agitation in Patients Undergoing Functional Endoscopic Sinus Surgery

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

Emergence agitation is one of the common postoperative complications after functional endoscopic sinus surgery(FESS). The objective of present study is to explore the effectiveness of butorphanol in the alleviation of emergence agitation in patients undergoing Functional Endoscopic Sinus Surgery.

NCT ID: NCT03360838 Recruiting - Clinical trials for Cognitive Impairment

Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool

CogCheck-Valid
Start date: April 16, 2018
Phase:
Study type: Observational

This observational cohort study is designed to validate the CogCheck application as a risk prediction tool for postoperative delirium in patients undergoing cardiac surgery.

NCT ID: NCT03347916 Recruiting - Clinical trials for Emergence Agitation After Desflurane Anesthesia

Gabapentin Oral Solution in Decreasing Desflurane Associated Emergence Agitation

Start date: January 5, 2017
Phase: N/A
Study type: Interventional

to study the effect of oral gabapentin (5 mg/kg) on emergence agitation after desflurane anesthesia in pediatrics undergoing starbismus surgery

NCT ID: NCT03330613 Recruiting - Emergence Delirium Clinical Trials

Emergence Delirium and Recovery Time in Children

Start date: November 15, 2017
Phase: N/A
Study type: Interventional

In this study, inhalation anesthesia procedure and intravenous anesthesia method will be compared in terms of emergence delirium and recovery time in children who are scheduled for dental treatment under general anesthesia.