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Clinical Trial Summary

The goal of this clinical trial is to compare Propofol versus Dexmedetomidine in children undergoing squint surgery. The main question it aims to answer is: • Which drug is more effective in preventing the appearance of Emergence Agitation in children after sevoflurane anesthesia in squint surgery, propofol or dexmedetomidine? Emergence agitation (EA) is a period of restlessness, agitation, inconsolable crying, disorientation, delusions, and hallucinations with impaired cognition and memory that commonly occurs in children undergoing ophthalmic surgery especially after Short acting volatile agents such as sevoflurane.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06312618
Study type Interventional
Source Ain Shams University
Contact Nada Mousa Helal, MSc
Phone 1091513200
Email nada.mousa@med.asu.edu.eg
Status Not yet recruiting
Phase Phase 4
Start date March 15, 2024
Completion date October 15, 2024

See also
  Status Clinical Trial Phase
Active, not recruiting NCT04807998 - Risk Factors for Pediatric Emergence Agitation and Analysis of Serum or Urine Metabonomics in Children With Agitation
Completed NCT00990769 - The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children N/A
Not yet recruiting NCT03596775 - Effect of Dexmedetomidine on Emergence Agitation and Postoperative Behavior Changes in Children Early Phase 1
Active, not recruiting NCT03846284 - Caudal Versus Intravenous Magnesium Sulfate on Emergence Agitation After Sevoflurane In Children. N/A
Completed NCT03062488 - Emergence Agitation and Pain Scores in Pediatrics When Comparing Single-modal vs Multi-modal Analgesia for ENT Surgery Early Phase 1
Completed NCT05601674 - The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty N/A
Completed NCT01737593 - Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia? Phase 4
Not yet recruiting NCT05624424 - Effect of Rematazolam Besylate, Propofol, and Sevoflurane Perioperative Sedation on Incidence of Emergence Agitation and Hemodynamics in Patients Undergoing Laparoscopic Abdominal Surgery Phase 4
Completed NCT04168879 - Sphenopalatine Ganglion Block for Nasal Surery N/A
Not yet recruiting NCT06079710 - Effect of Intraoperative and Awakening Electroencephalogram on Awakening Agitation After General Anesthesia in Children
Recruiting NCT04142840 - Dexmedetomidine and Propofol in the Treatment of Emergence Agitation Early Phase 1
Completed NCT04844333 - Effect of Extubation Under Deep Anesthesia on Emergence Agitation of Nasal Surgery N/A
Recruiting NCT02169843 - Small Doses of Dexmedetomidine for Emergence Agitation Phase 4
Completed NCT04820595 - Postoperative Neurocognitive Dysfunction: Is There Any Place for Emergency Agitation: A Prospective Cohort Trial
Recruiting NCT05766436 - Nebulized Dexmedetomidine VS ODF Melatonin for Peri Operative Anxiety and Emergence Agitation in Pediatric Day Surgery N/A
Completed NCT03134547 - A Comparison of Emergence Agitation by Sevoflurane for Intraoperative Sedation Associated With Caudal Block N/A
Completed NCT03807011 - Emergence Agitation in Pediatric Strabismus Surgery N/A
Completed NCT04485273 - Effect of Dexmedetomedine in Subtenon's Block on Emergence Agitation in Pediatric Strabismus Surgery N/A
Completed NCT03179293 - Transition to Propofol After Sevoflurane Anaesthesia to Prevent Emergence Agitation Phase 4
Completed NCT05223010 - Melatonin for Pediatric Emergence Agitation Phase 4