Emergence Agitation Clinical Trial
Official title:
Comparing the Efficacy of Dexmedetomidine and Propofol in the Treatment of Emergence Agitation Occurring in Adults After General Anesthesia: A Randomised Control Trial DP-TEA Trial
1. This clinical research aims to compare the effects of dexmedetomidine and propofol on
the treatment of emergence agitation in adult patients after general anesthesia.
2. Half of participants will receive dexmedetomidine while the other half will receive
propofol when emergence agitation happens.
As a common problem observed in pediatric patients after sevoflurane anesthesia, emergence
agitations are investigated mainly in children.For adults,previous studies were almost about
the efficacy of premedication on preventing emergence agitation. Once emergence agitation
happens, there is still no guidelines established to recommend the medication usage in the
post-anaesthesia care unit.So high-quality prospective clinical studies are required to
provide evidence for emergence agitation treatment.
Dexmedetomidine and propofol are both widely used in general anesthesia and can be acquired
easily.When emergence agitation occurs,both injections are common choices in daily clinical
administration on emergence agitation.To the investigator's knowledge ,propofol with a very
quick onset is superior for anesthesia goals, but is without analgesia effects.While
dexmedetomidine can produce sedation,analgesia,anxiolysis.So the investigators propose the
hypothesis here that dexmedetomidine is prior to propofol on the treatment of emergence
agitation in adults patients after general anesthesia.Therefore this research is undertaken
to verify the hypothesis.
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Status | Clinical Trial | Phase | |
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Active, not recruiting |
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