Effect of Degranulation Needle With Different Diameters on the Rate Good Embryo in IVF

Embryo Clinical Trial

Official title:

Effect of Degranulation Needle on the Rate Good Embryo in IVF

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03810040
• Other study ID #: 123456
• Status: Not yet recruiting
• Phase: N/A
• Start date: February 2019
• Est. completion date: November 2019

Study information

• Verified date: January 2019
• Source: Tang-Du Hospital
• Contact: wang ming
• Phone: 8613259809290
• Email: wangmingbio[@]snnu.edu.cn
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.

Description:

Good-quality embryos are critical for the success of in vitro fertilization (IVF). But, to date, there is no report of the effect of different diameters denuding pipette on the embryos quality. To investigate the effect of denuding pipette in IVF outcomes, we plan to recruit women undergoing IVF treatment cycles and classified them into two groups according to the different diameters. The participants were divided into two group. Odd-numbered days the zygotes were degranulated with the 140 microns needles. Even-numbered days the zygotes were degranulated with the 150 microns needles. Consequently, the rate of fertilization, zygotes cleaved, top quality embryos on D3, and blastocysts obtained were recorded.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 400
• Est. completion date: November 2019
• Est. primary completion date: May 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 22 Years to 35 Years

Eligibility

Inclusion Criteria:

• first cyele of IVF treatment

Exclusion Criteria:

• oocyte number less than 4

• oocyte number over than 25

Related Conditions & MeSH terms

• Embryo

Intervention

Device:
• 140 microns denuding pipette
the degranulated needle size was 140 microns
• 150 microns denuding pipette
the degranulated needle size was 150 microns

Locations

Country	Name	City	State
China	Tangdu Hospital	Xi'an	Shaanxi

Sponsors (1)

Lead Sponsor	Collaborator
Tang-Du Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	quality of embryo	embryo quality assessed by good embryo rate	one year
Secondary	clinical outcome - clinical prengancy rate	clinical prengancy rate	three years