Embryo Aneuploidies and Ovarian Stimulation

Embryo Aneuploidies Clinical Trial

Official title: Incidence of EmbyoO Aneuploidies in Natural Versus Stimulated Cycles in the Same Women.

Status Completed

Clinical Trial Summary

There is a considerable concern about the effects of controlled ovarian hyperstimulation (COH) for In Vitro Fertilization- Embryo Transfer (IVF-ET) on embryo quality and on the incidence of chromosomal abnormalities in oocytes and embryos.

The main question remaining is if COH may increase the aneuploidies rate in young and healthy women. Therefore, the primary endpoint of the present study is to analyse the incidence of chromosomal abnormalities in this group of patients (oocyte donors), either in oocytes obtained after a natural cycle or in those retrieved after a COH cycle. To get rid of the male factor influence, donated sperm will be used.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Aneuploidy
• Embryo Aneuploidies

• NCT number: NCT00707525
• Study type: Interventional
• Source: Instituto Valenciano de Infertilidad, IVI VALENCIA
• Status: Completed
• Phase: Phase 4
• Start date: February 2008
• Completion date: February 2010