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Elevated Intraocular Pressure clinical trials

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NCT ID: NCT05165290 Active, not recruiting - Clinical trials for Elevated Intraocular Pressure

Prospective, Double-masked, Randomized, Multi-center, Active-controlled, Parallel-group, 3-month Study Assessing the Safety & Ocular Hypotensive Efficacy of TC-002 Ophthalmic Solution Compared to Latanoprost Ophthalmic Solution 0.005% in Subjects With Elevated Intraocular Pressure

TC-002-301
Start date: November 29, 2021
Phase: Phase 3
Study type: Interventional

Prospective, double-masked, randomized, multi-center, active-controlled, parallel-group, 3-month study assessing the safety and ocular hypotensive efficacy of TearClear latanoprost Ophthalmic Solution, 0.005% (TC-002) compared to latanoprost Ophthalmic Solution, 0.005% (LAT) in subjects with elevated intraocular pressure at approximately 20 study sites located in the United States

NCT ID: NCT01896180 Completed - Ocular Hypertension Clinical Trials

Study to Compare the Safety and Efficacy of ALZ-1101 to Latanoprost in Patients With Intraocular Pressure Inadequately Controlled by Latanoprost

Start date: July 2013
Phase: Phase 2
Study type: Interventional

This is a pilot, proof of concept study to evaluate the safety and efficacy of ALZ-1101 dosed once daily for 28 days compared to latanoprost 0.005% ophthalmic solution in patients with elevated intraocular pressure not adequately controlled with latanoprost.

NCT ID: NCT00902200 Completed - Clinical trials for Elevated Intraocular Pressure

A Study of AR-12286 in Patient With Elevated Intraocular Pressure (IOP)

Start date: May 2009
Phase: Phase 2
Study type: Interventional

Double-masked, randomized, multi-center, placebo-controlled parallel-comparison of AR-12286.

NCT ID: NCT00409669 Recruiting - Clinical trials for Elevated Intraocular Pressure

Intraocular Pressure Accuracy and Variability of the Barraquer Tonometer

Start date: November 2006
Phase: N/A
Study type: Interventional

To determine if the Barraquer tonometer provides an accurate and reliable measurement of intraocular pressure. The Barraquer tonometer is a device used to safely and painlessly measure intraocular pressure.

NCT ID: NCT00307918 Terminated - Clinical trials for Elevated Intraocular Pressure

Acupuncture for Elevated Intraocular Pressure

Start date: May 2006
Phase: Phase 3
Study type: Interventional

Glaucoma is the leading cause of irreversible blindness in the world, resulting from progressive axonal destruction of the optic nerve. Primary open-angle glaucoma is the most common form, and it is usually painless with insidious onset. Conventional treatment is focused on lowering intraocular pressure (IOP), the one risk factor that can be modified, which has been demonstrated to protect against further damage to the optic-nerve head. Acupuncture is an ancient treatment which has been found to be beneficial for many ailments, and may reduce IOP. We propose a pilot study to evaluate whether acupuncture is an effective and safe modality for reducing elevated IOP in patients with open angle glaucoma and primary ocular hypertension. Patients with elevated IOP on tonometric measurement (20mmHg < IOP < 30mmHg) will be treated twice-weekly with a standardized (as opposed to individualized) acupuncture treatment. Treatment will last for four-weeks (for a total of 8 treatments), and patients will be evaluated for IOP diurnal curves at 2 weeks (4 treatment), 4 weeks (end of treatment ) and then 4 weeks following the last treatment.