Critical Care Clinical Trial
Official title:
Sedation Monitoring Using Frontal Electroencephalogram, Electromyogram and Hemodynamic Responses to Pain in Critical Care
Purpose: Assessing nociception and sedation in mechanically ventilated patients in the ICU is
challenging, with few reliable methods available for continuous monitoring. Measurable
cardiovascular and neurophysiological variables, such as blood pressure, heart rate, frontal
EEG, and frontal EMG, might provide a medium for sedation and nociception monitoring. The
hypothesis of this explorative study is that the aforementioned variables correlate with the
level of sedation, as described by the Richmond Agitation-Sedation score (RASS).
Methods: Thirty adult postoperative ICU patients on mechanical ventilation and receiving
intravenous sedation, excluding patients with primary neurological disorders, head injury, or
need for continuous neuromuscular blockage. Continuous measurements of bispectral index
(BIS), EMG power (EMG), EMG-derived Responsiveness Index (RI), averaged blood pressure
variability (ARV), and Surgical Pleth Index (SPI) were tested against repeated RASS
measurements, and separately against responsiveness to painful stimuli at varying RASS
levels.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05114551 -
ICU Predictive Score of WEaning Success in Patients At Risk of Extubation Failure
|
||
Completed |
NCT05547646 -
The Prevalence of Healthcare-associated Infection in Medical Intensive Care Units in Tunisia
|
||
Recruiting |
NCT03697785 -
Weaning Algorithm for Mechanical VEntilation
|
N/A | |
Completed |
NCT02922101 -
Evaluation of the Effectiveness of an Audit and Feedback Intervention With Quality Improvement Toolbox in Intensive Care
|
N/A | |
Completed |
NCT02902783 -
DONATE-Pilot Study on ICU Management of Deceased Organ Donors
|
||
Completed |
NCT01885442 -
TryCYCLE: A Pilot Study of Early In-bed Leg Cycle Ergometry in Mechanically Ventilated Patients
|
N/A | |
Completed |
NCT01857986 -
Evaluating Air Leak Detection in Intubated Patients
|
N/A | |
Recruiting |
NCT05518955 -
VR Integrated Into Multicomponent Interventions for Improving Sleep in ICU
|
N/A | |
Recruiting |
NCT03810768 -
Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness
|
||
Completed |
NCT03295630 -
Validity of an Actigraph Accelerometer Following Critical Illness
|
N/A | |
Completed |
NCT05556811 -
HEaling LIght Algorithms for the ICU Patient
|
N/A | |
Recruiting |
NCT05702411 -
Air Stacking Technique For Pulmonary Reexpansion
|
N/A | |
Completed |
NCT02741453 -
Bilateral Internal Jugular Veins Ultrasound Scanning Prior to CVC Placement
|
N/A | |
Recruiting |
NCT04979897 -
Impact on Mental, Physical, And Cognitive Functioning of a Critical Care sTay During the COVID-19 Pandemic
|
||
Completed |
NCT05281224 -
Ventilator Tube Holder for Patients With a Tracheostomy
|
||
Withdrawn |
NCT02970903 -
VitalPAD: an Intelligent Monitoring and Communication Device to Optimize Safety in the PICU
|
N/A | |
Recruiting |
NCT02587273 -
The Pharmacokinetics of Fentanyl in Intensive Care Patients
|
Phase 4 | |
Completed |
NCT02661607 -
Point of Care Echocardiography Versus Chest Radiography for the Assessment of Central Venous Catheter Placement
|
N/A | |
Completed |
NCT01479153 -
Venous Site for Central Catheterization
|
N/A | |
Recruiting |
NCT06110390 -
High-flow Nasal Oxygen Therapy to Prevent Extubation Failure in Adult Trauma Intensive Care Patients
|
N/A |