Immediate Effect of Electrical Noise Stimulation on Neuromuscular Adaptation of Balance

Electroencephalography Clinical Trial

Official title:

Immediate Effect of Electrical Noise Stimulation on Neuromuscular Adaptation During Single-Leg Stance in Healthy Young

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT05570890
• Other study ID #: YM111060E
• Status: Enrolling by invitation
• Phase: N/A
• Start date: April 29, 2022
• Est. completion date: January 31, 2023

Study information

• Verified date: July 2022
• Source: National Yang Ming University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Noise stimulation had an immediate effect on improving balance control. The present study aimed to clarify the immediate neuromuscular adaptation induced by noise stimulation and find the correlation between neuromuscular adaptation and functional performance.

Description:

The mechanism behind noise stimulation is called Stochastic Resonance which improves the detectivity of sensory input with the presence of noise, making sub-sensory threshold input detectable. Noise stimulation had been proved to improve postural control, Ia afferent sensitivity, and muscle activity of the tibialis anterior. With this evidence of the effect of noise stimulation on balance enhancement, the neuromuscular adaptation induced by noise stimulation has not been researched yet. Therefore, the present study aims to clarify the immediate effect of noise on neuromuscular regulation during postural control.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 20
• Est. completion date: January 31, 2023
• Est. primary completion date: November 30, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 40 Years

Eligibility

Inclusion Criteria:

• age between 20 and 40 years old
• without ankle injury history in 1 year
• without musculoskeletal or neurological diseases that would affect balance performance
• without visual impairment (except vision correction or no visual problems)
• without vestibular impairment.

Exclusion Criteria:

• subject who cannot tolerate the cutaneous electrical stimulation to induce H reflex
• single-leg stance (SLS) without support is shorter than 80 secs

Related Conditions & MeSH terms

• Electroencephalography
• Electromyography

Intervention

Device:
• electrical noise stimulation
The intensity of electrical noise stimulation will be set at 90% of the sensory threshold of each participant.
• Sham stimulation
Participants will not receive stimulation.
• Foam
The foam will be used to make an unstable surface.

Locations

Country	Name	City	State
Taiwan	National Yang-Ming University	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Yang Ming University

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mean sway path of the center of pressure	The mean sway path in mm will represent balance performance	40 seconds under each condition
Primary	Mean sway velocity of the center of pressure	The mean sway velocity in mm/sec will represent balance performance	40 seconds under each condition
Primary	Cortical excitability	Power spectrum density of EEG will calculated for representing cortical excitability.	40 seconds under each condition
Primary	Spinal reflex excitability	H reflex amplitude will represent the excitability of peripheral control from spinal level nerve system.	40 seconds under each condition
Primary	Co-activation index	Co-activation index will be calculated by EMG activity of Tibialis Anterior and Soleus muscle to represent the muscle activity.	40 seconds after each condition