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Electric Impedance clinical trials

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NCT ID: NCT04359407 Completed - Clinical trials for Severe Acute Respiratory Syndrome Coronavirus 2

Prone Positioning and Regional Ventilation in Mechanically Ventilated COVID-19 Patients

COVID-19_EIT
Start date: April 27, 2020
Phase:
Study type: Observational

The consensus therapeutic strategy implies that COVID patients with acute lung injury due to coronavirus are routinely placed in prone position in an attempt to improve oxygenation by increasing ventilation homogeneity. The purpose of the study is to quantify with the electrical impedance tomography (EIT) the changes in the ventilation and aeration in the dorsal regions of the lung when the patient is placed in prone position.

NCT ID: NCT04269291 Completed - Healthy Volunteers Clinical Trials

An Investigation Into an Objective Measure of Muscle Quality, Function and Ability

Start date: June 18, 2020
Phase:
Study type: Observational

The assessment of muscular function, quality and ability is of high importance in a diverse range of clinical disciplines from anaesthetics to physiotherapy. This study will look at the range of measurement techniques currently in use and development and considers their effectiveness and objectivity. It will also investigate whether an objective measurement technique can be found or developed that can be used both in the clinical environment and the community setting. This will focus on upper limb function and ability; ability is used here instead of strength since ability better describes functions needed for daily living rather than the maximum output a muscle is capable of.

NCT ID: NCT03410771 Completed - Pharmacokinetics Clinical Trials

Bioelectrical Impedance Analysis as a Bedside Tool to Estimate Volume of Distribution of Hydrophilic Antimicrobials in Critically Ill Patients

Start date: October 1, 2015
Phase: N/A
Study type: Observational

Bioelectrical impedance analysis is studied as a bedside tool to estimate capillary leak in order to guide dosing of hydrophilic antimicrobials.

NCT ID: NCT02603783 Completed - Pain Measurement Clinical Trials

Esophageal capsaïcin Infusion and Mucosal Integrity

Start date: November 2015
Phase: N/A
Study type: Interventional

Reflux is common, especially after large meals. In general, this can do no harm. However, if reflux occurs often and causes troublesome symptoms and or complications, it is called gastroesophageal reflux disease (GERD). Long exposure to gastric acid causes the mucosa of the esophagus to loose its integrity, which is thought to lead to the symptom of heartburn. Several food products can also impair the esophageal mucosa integrity and thereby influence reflux symptoms. One of these products is capsaicin, the pungent ingredient of red peppers. Use of capsaicin often leads to worsening of complaints in patients with GERD and can cause symptoms in healthy volunteers, possibly due to its effect on the mucosal integrity. In this study the investigators want to investigate the effect of capsaicin infusion on mucosal integrity. The investigators will evaluate mucosal impedance and the histology of the esophageal mucosa. In addition, the investigators also aim to assess the involvement of the TRPV1 receptor by evaluating the possible release of neuropeptides in the esophageal mucosa.