Influence of Corticoids on Renal Function in Cardiac Surgery

Elective Cardiac Surgery Clinical Trial

Official title:

Influence of Corticoids on Renal Function in Cardiac Surgery

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00879931
• Other study ID #: 2006/031
• Status: Completed
• Phase: Phase 2
• Start date: January 2013
• Est. completion date: July 2015

Study information

• Verified date: December 2022
• Source: University Hospital, Ghent
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Hypothesis: Corticoid treatment in cardiac surgery works renal protective.

Study design: Randomized, double blind trial in which one group of patients will receive methylprednisolone and the other group (control) will receive placebo NaCl 0.9%.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 80
• Est. completion date: July 2015
• Est. primary completion date: July 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 80 Years

Eligibility

Inclusion Criteria:

• age between 20-80 year

• patients scheduled for elective cardiac surgery.

• preoperative creatinine levels of < 2mg/dl

• no corticoid treatment

Exclusion Criteria:

• non-elective surgery

• patiënts with renal dysfunction: creatinine > 2mg/dl

• patiënts treated with corticoids

Related Conditions & MeSH terms

• Elective Cardiac Surgery

Intervention

Drug:
• Methylprednisolone
Methylprednisolone
• Placebo
Placebo (NaCl 0.9%)

Locations

Country	Name	City	State
Belgium	University Hospital Ghent	Ghent

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Ghent

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Renal dysfunction and renal failure postoperatively in cardiac surgery		within 48 hours after cardiac surgery

External Links

•   Website of the University Hospital Ghent