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Apatinib in Recurrent or Refractory Intracranial Central Nervous System Malignant Tumors

Efficacy and Safety Clinical Trial

Official title:
Efficacy and Safety of Apatinib Combined With Dose-dense Temozolomide in Recurrent Glioblastoma

Clinical Trial Summary

The patient was given a daily dose of apatinib 500mg (or based on weight). Individualized chemotherapy regimens were given based on molecular expression and prior chemotherapy.

Clinical Trial Description

The patient was given a daily dose of apatinib 500mg (or based on weight). Individualized chemotherapy regimens were given based on molecular expression and prior chemotherapy. Brain MRI+MRS was examined every 3 months; Blood routine, urine routine and liver and kidney function were examined once a week. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03660761
Study type Interventional
Source Shandong Cancer Hospital and Institute
Contact
Status Completed
Phase Phase 2
Start date March 3, 2016
Completion date January 6, 2018
View Details
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