Clinical Trials Logo
  1. Home
  2. Effects of Immunotherapy
  3. NCT05468307

Study on TIL Engineered With Membrane-Binding Cytokine for the Treatment of Advanced Gynecologic Tumors

Treatment Side Effects Clinical Trial

Official title:
A Clinical Study on TIL Engineered With Membrane-Binding Cytokine for the Treatment of Advanced Gynecologic Tumors

Clinical Trial Summary

This study is to investigate the safety and efficacy on TIL engineered with membrane-binding cytokine (GC203 TIL) for the treatment of patients with advanced gynecologic tumors. Autologous TILs from tumor resections or biopsies are first gene modified (engineered with membrane-binding cytokine) and than expanded before i.v. infusion into the patient after NMA lymphodepletion treatment with cyclophosphamide.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05468307
Study type Interventional
Source Shanghai Juncell Therapeutics
Contact Clinical GC
Phone 086-18001759113
Email clinicaltrials@juncell.com
Status Recruiting
Phase Early Phase 1
Start date March 10, 2022
Completion date March 10, 2025
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05098197 - Study on TIL for the Treatment of Advanced Hepatobiliary-Pancreatic Cancers Early Phase 1
Recruiting NCT05098184 - Study on TIL for the Treatment of Advanced Melanoma Early Phase 1
Recruiting NCT05098171 - Study on Signal Switch Receptor Modified TIL for the Treatment of Advanced Gynecologic Tumors Early Phase 1
Not yet recruiting NCT03807388 - ReMindCare App for Patients From First Episode of Psychosis Unit. N/A
Recruiting NCT06057350 - Surgery Versus Endoscopic Resection for Incompletely Removed Early Colon CAnceR N/A
Recruiting NCT05084625 - PACED-digitized Support During Adjuvant Endocrine Therapy N/A
Recruiting NCT05092074 - Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) for Patients With Hepatitis C Virus Infection
Active, not recruiting NCT04986670 - NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer N/A
Recruiting NCT05142475 - Study on TIL for the Treatment of Advanced Breast Cancer Early Phase 1
Completed NCT04913350 - Contralateral Effects of Russian Current on Adolescent Athlete N/A
Terminated NCT04004884 - Liver Safety Assessment During Ulipristal Acetate Treatment for Uterine Fibroids (LISA)
Recruiting NCT04768582 - Platelet Reactivity After an Eastern Asian Loading Dose of Prasugrel in Taiwanese ACS Patients N/A
Recruiting NCT05767866 - Assessing an Oral EGFR Inhibitor,YK-209A in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR Phase 1/Phase 2
Recruiting NCT06340516 - NT-proBNP to Assess Trastuzumab-induced Cardiotoxicity N/A
Recruiting NCT06315582 - Surgical Approach to Uterine Septum N/A
Not yet recruiting NCT05085808 - RCT: Trazodone vs Quetiapine vs Placebo for Treating ICU Delirium (TraQ) Phase 4
Recruiting NCT04923100 - Therapeutic Effect of New Biologics in Crohn's Disease
Recruiting NCT05446051 - Development and Testing of a TTDSS for Cancer Patients N/A
Recruiting NCT05030701 - Toxicity of Treatments for Non-tuberculous Mycobacterial Infections in Cancer Patients or Not
Recruiting NCT05492487 - A Pilot Study on Fertility Conservative Treatment of Atypical Endometrial Hyperplasia in Singapore Phase 2