Acclimatization of Healthy Subjects During a Stay at 3200 m

Effects of High Altitude Clinical Trial

Official title:

Acclimatization of Healthy Subjects During a Stay at 3200 m

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02451020
• Other study ID #: EK15-2015_V2
• Status: Completed
• Phase: N/A
• Start date: June 8, 2015
• Est. completion date: August 9, 2015

Study information

• Verified date: October 2018
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The study evaluates respiratory acclimatization in healthy lowlanders staying for 3 weeks at 3200 m.

Description:

This study evaluates the effect of 3 weeks altitude acclimatization on sleep related breathing disturbances in healthy subjects staying at 3200 m. Participants living in Bishkek, Kyrgyzstan (700 m), will be transferred by car within 4 h to the Tuja Ashu high altitude clinic (3200 m). Outcomes will be assessed repeatedly during the stay at 3200 m.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: August 9, 2015
• Est. primary completion date: August 9, 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years to 75 Years

Eligibility

Inclusion Criteria:

• Perfect health

• Born, raised and currently living at low altitude (<800m)

• Informed consent.

Exclusion Criteria:

• Any acute or chronic disease

• heavy smoking (>20 cigarettes per day).

Related Conditions & MeSH terms

• Altitude Sickness
• Effects of High Altitude

Intervention

Other:
• Altitude exposure
Participants will stay for 3 weeks at an altitude of 3200 m

Locations

Country	Name	City	State
Kyrgyzstan	National Center of Cardiology and Internal Medicine	Bishkek

Sponsors (2)

Lead Sponsor	Collaborator
University of Zurich	National Center of Cardiology and Internal Medicine, Kyrgyzstan

Country where clinical trial is conducted

Kyrgyzstan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mean nocturnal oxygen saturation measured by pulse oximetry	Difference in mean nocturnal oxygen saturation between night 1 and night 7	night 7 at 3200 m
Secondary	Mean nocturnal oxygen saturation measured by pulse oximetry	Difference in mean nocturnal oxygen saturation between night 1 at 3200 and night 1 at 700 m	night 1 at 3200 m
Secondary	Mean nocturnal oxygen saturation measured by pulse oximetry	Difference in mean nocturnal oxygen saturation between night 21 and night 1 at 3200 m	night 21 at 3200 m
Secondary	Mean nocturnal oxygen saturation measured by pulse oximetry	Mean nocturnal oxygen saturation during night 1 at 700 m	night 1 at 700 m (low altitude baseline)