Effect of High Altitude Clinical Trial
Official title:
Asthma Rehabilitation at High vs. Low Altitude: Randomized Controlled Parallel-group Trial
prospective controlled interventional trial evaluating the efficacy of a 3-weeks asthma rehabilitation program at high altitude (3200m) and low altitude (760m) on lung function and asthma control.
Low altitude baseline measurements will be performed in Bishkek. Participants will then
either be assigned to a rehabilitation program in Bishkek (760m) or in Tuja Ashu (3200m).
The rehabilitation programs in high or low altitude will be identically performed and will
comprise
- asthma education and awareness
- instruction on inhaled therapies
- smoking cessation counseling
- respiratory and skeletal muscle training in groups
- guided walks / cycle ergometer training
- questionnaires on asthma control, quality of life
- spirometry and peak flow measurements
- echocardiography
Measurement on study subjects will be performed at baseline (Bishkek), during the
rehabilitation program, after completion of the rehabilitation program and during a
follow-up at week 15.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
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