Edentulous Jaw Clinical Trial
Official title:
Evaluation of a Bioactive Surface in Post-extraction Sites: Case Control Study
In this case-control study a bioactive implant surface was compared with traditional surfaced implants. Primary objectives: Test the implant stability in post-extractive sites, comparing traditional surfaced implants (MultiNeO CS, control group) to bioactive surfaced implants (NINA- MultiNeO NH, treatment group). Primary outcome endpoints were Implant stability, assessed through Implant stability quotient (ISQ) values and Marginal bone loss (MBL)
In this post- market case control study, the tested CE-marked dental implants are MultiNeO CS 1930 and NINA MultiNeO NH 9330, both manufactured by Alpha-Bio Tec. . Alpha-Bio Tec. implants systems are made of Ti-6AI-4V ELI Titanium alloy which is a high-performance and highly biocompatible alloy for manufacturing bone implants. Alpha-Bio Tec developed the superior NanoTec&trade implant surface for optimized osseointegration process. Alpha-Bio Tec NanoTecâ„¢ implant surface is achieved by a complex process of large particle sandblasting and acid etching. Sandblasting with large particles allows the creation of macropores (20-40 microns), while the double etching allows the creation of micropores (1-5 microns). The micro - structure and roughness properties of NanoTecâ„¢ Implant Surface greatly influences the dynamic wettability of implant surfaces during the initial contact with the host. The overwritten implant surface enables greater absorption of blood and plasma proteins directly inside the micropores, immediately after the implant has been placed. It is the implant surface of MultiNeO. NeO or MultiNeO is defined as a system since it includes three types of connections: a conical narrow connection (CHC), a conical standard conical connection (CS) and an Internal Hex connection (IH). the fixture has a straight coronal part, a slightly tapered body and a conical apical part. We will use MultiNeO CS in control group. One of the MultiNeO biggest clinical advantages since it is as good at bone type 4 as it is at bone type 1, 2 or 3. Topography and surface roughness of MultiNeO lead to some clinical advantages: Increased early BIC; Increased primary and secondary stability; Shortened healing period; Accelerated and improved osseointegration process. MultiNeO CS has an implant surface similar to the aforementioned SLA surface manufactured by Straumann. In fact, SLA is a sub-micron scale roughness created by Aluminum oxide blasting and double acid etching. NINA- MultiNeO NH is used for treatment group, and it is being tested. NINA MultiNeO NH has got an innovative bioactive surface. NINA MultiNeO NH surface is a combination of the abovementioned roughening process and the creation of titanium oxide nano structure. Its hydrophilic part is created by resorbable salt thus maintaining its hydrophilicity. Although a variety of implant surface are available for implant rehabilitation, the first hypothesis is that NINA MultiNeO NH Alpha-Bio Tec ® will be positively adopted for rehabilitation of missing teeth with shorter healing time and less marginal bone loss. The idea behind these studies is to maximize the effect of the bioactive surface testing its behavior in a poor host environment with a reduced time ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Active, not recruiting |
NCT05082038 -
Mandibular Full-arch Rehabilitation With Internal Hexagonal and Conical Connection Implants
|
N/A | |
Completed |
NCT01411683 -
Mandibular Overdentures Retained by Conventional or Mini Implants
|
N/A | |
Completed |
NCT05924451 -
Study of Hard and Soft Tissue Behavior Around Abutments on Implants.
|
N/A | |
Completed |
NCT04851002 -
Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
|
N/A | |
Completed |
NCT01230320 -
Simplified vs. Conventional Methods for Complete Denture Fabrication
|
N/A | |
Active, not recruiting |
NCT05062863 -
An Observational Clinical Study of the T3 Dental Implant System
|
||
Active, not recruiting |
NCT04354688 -
T3 Certain Tapered With DCD vs T3 Certain Tapered Non-DCD
|
N/A | |
Not yet recruiting |
NCT06152432 -
Maxillary Implant Overdentures Retained by Bars or Locator
|
N/A | |
Completed |
NCT06209814 -
Evaluation of Open-face Maxillary Complete Denture for Patients With Prominent Premaxilla
|
N/A | |
Recruiting |
NCT04662333 -
Adjunctive Benefit of Xenograft Plus a Membrane During Sinus Crestal Approach
|
N/A | |
Active, not recruiting |
NCT04236336 -
A Clinical Study of the TSV Dental Implant System
|
||
Active, not recruiting |
NCT04237545 -
A Clinical Study of the T3 Short Dental Implant System
|
N/A | |
Not yet recruiting |
NCT03674554 -
Prosthetic Complications of Screw Retained Restoration
|
N/A | |
Not yet recruiting |
NCT06155630 -
3D Printing for the Fabrication of Mandibular Implant Overdentures
|
N/A | |
Recruiting |
NCT04429373 -
Effect of Platelet-rich Plasm (PRF) on Two-implant Mandibular Overdenture: a Split Mouth
|
N/A | |
Completed |
NCT06146153 -
Intra Oral Scanning of Edentulous Arches
|
||
Completed |
NCT05777980 -
Effect of Prosthetic Rehabilitation on Nutritional Status of Geriatric Patients
|
||
Completed |
NCT03992300 -
Comparison of Full-arch Implant-supported Frameworks From an Intraoral Scanning or From a Conventional Impression
|
N/A | |
Completed |
NCT03538184 -
Molecular Content of Peri-implant Sulcus During Wound Healing and Osseointegration Following Drilling and Piezosurgery
|
N/A | |
Not yet recruiting |
NCT06393582 -
Accuracy Evaluation of Implant Impressions: A Prospective Study
|
N/A |