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Clinical Trial Summary

This is a single-centre, observational cohort study with the following objectives: Firstly, the investigators aim to evaluate the vision-related quality of life and mental health status in congenital ectopia lentis patients. Secondly, the investigators target to investigate the correlations between genotype and clinical phenotype in patients of congenital ectopia lentis. Thirdly, to explore the metabolic profiles in the aqueous humor (AH) of patients with congenital ectopia lentis. Lastly, this study aims to explore the longitudinal changes of ocular biological parameters and complications in patients with postoperative congenital ectopia lens in the Chinese population.


Clinical Trial Description

Congenital ectopia lens is a rare ophthalmic disease that seriously harms the physical and mental health of patients. Surgery is the only definite treatment at present. However, the changes in vision-related quality of life, mental health status, ocular biological parameters postoperative congenital dislocation of lens have not been systematically studied in the Chinese population. In this trial, the investigators aim to evaluate the vision-related quality of life and mental health status in congenital ectopia lentis patients, investigate the correlations between genotype and clinical phenotype in patients of congenital ectopia lentis, explore the metabolic profiles in the aqueous humor (AH) of patients with congenital ectopia lentis, and explore the longitudinal changes of ocular biological parameters and complications in patients with postoperative congenital ectopia lens in the Chinese population. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05654025
Study type Observational
Source Zhongshan Ophthalmic Center, Sun Yat-sen University
Contact Dangying Zheng, M.D
Phone 020-87330478
Email zhengdyy@163.com
Status Recruiting
Phase
Start date December 5, 2022
Completion date December 2027

See also
  Status Clinical Trial Phase
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Completed NCT04319107 - Classifying Ectopia Lentis in Marfan Syndrome Into Five Grades of Increasing Severity
Recruiting NCT05628129 - Effect of Mobile Communication on Congenital Ectopia Lentis Follow-up Adherence N/A