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Effects of Topical Vitamin K, Vitamin K and Retinol, and Arnica on Post-Laser Bruising

Ecchymosis Clinical Trial

Official title:
Effects of Topical Vitamin K, Vitamin K and Retinol, and Arnica on Post-Laser Bruising

Clinical Trial Summary

The objective of this study is to assess the comparative utility of topical formulations in hastening the resolution of skin bruising. For each subject, four standard bruises of 7 mm diameter each were created on the bilateral upper inner arms, 5 cm apart, two per arm, using a 595-nm pulsed-dye laser. Randomization was used to assign one topical agent (5% vitamin K, 1% vitamin K and 0.3% retinol, 20% arnica or white petrolatum) to exactly one bruise per subject, which was then treated under occlusion twice a day for 2 weeks. A dermatologist rated bruises in standardized photographs immediately after bruise creation and at week 2.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00363038
Study type Interventional
Source Northwestern University
Contact
Status Completed
Phase N/A
Start date July 2006
Completion date August 2006
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