Personalized Treatment

Eating Disorders Clinical Trial

— PT  

Official title:

Feasibility of Network-Informed Personalized Treatment for Eating Disorders

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04183894
• Other study ID #: IRB# 18.0622
• Status: Completed
• Phase: N/A
• Start date: November 2, 2018
• Est. completion date: January 23, 2023

Study information

• Verified date: April 2023
• Source: University of Louisville
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The Personalized Treatment Study creates an individualized network of symptoms for a participant with a current eating disorder. This network will be used to develop a personalized treatment intervention. This study aims to 1) determine if personalized treatments can be conducted using a network analysis of patient symptoms, and 2) to assess the effectiveness of network-informed personalized treatment for participants with eating disorders.

Description:

Cognitive behavioral theory proposes that cognitions, behaviors, affect, and physiological symptoms interact with each other to maintain and exacerbate psychiatric disorders (Beck, 2011). Network theory identifies core symptoms that maintain and promote the spread of ED psychopathology within individuals (Borsboom & Cramer, 2013). Once identified, core "trigger" symptoms can be directly targeted to disrupt the spread or "activation" of ED behaviors, which would help patients achieve full recovery, and ultimately, prevent relapse. One of the main goals of the Personalized Treatment Study is to create an individualized network for a participant with a current eating disorder, which can be used to develop a personalized treatment intervention. Our research questions are: 1) Can a personalized treatment plan be conducted from a network analysis of patient symptoms, and 2) How effective is this personalized treatment based off of a network of symptoms.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 59
• Est. completion date: January 23, 2023
• Est. primary completion date: January 23, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Current eating disorder diagnosis

• at least 18 years of age,

• not actively suicidal,

• not manic,

• not psychotic

Exclusion Criteria:

• No current eating disorder diagnosis,

• younger than 18 years of age,

• active psychosis,

• active mania, or

• actively suicidal.

Related Conditions & MeSH terms

• Disease
• Eating Disorder Symptom
• Eating Disorders
• Feeding and Eating Disorders

Intervention

Behavioral:
• Personalized Intervention
Participants will receive a personalized intervention based on their personalized network.

Locations

Country	Name	City	State
United States	University of Louisville	Louisville	Kentucky

Sponsors (1)

Lead Sponsor	Collaborator
University of Louisville

Country where clinical trial is conducted

United States, 

References & Publications (2)

Beck, J. S. (2011). Cognitive-behavioral therapy. Clinical textbook of addictive disorders, 491, 474-501.

Borsboom D, Cramer AO. Network analysis: an integrative approach to the structure of psychopathology. Annu Rev Clin Psychol. 2013;9:91-121. doi: 10.1146/annurev-clinpsy-050212-185608. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Eating Disorder Symptoms	Changes in eating disorder symptoms will be measured at one month, six month, and 1 year follow-up questionnaires.	Prior to, during, and after personalized intervention through approximately one year.