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Early Life Adversity clinical trials

View clinical trials related to Early Life Adversity.

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NCT ID: NCT05690256 Recruiting - Caregiver Stress Clinical Trials

The Resilience Clinic Evaluation

Start date: May 25, 2023
Phase: N/A
Study type: Interventional

Early life adversity can affect children's physical and mental health. The Resilience Clinic is a support program for young children and their caregivers who have been exposed to significant adversity, aiming to prevent the harmful effects of stress and improve child health, behavior, and development while also reducing caregiver stress. This study seeks to evaluate the Resilience Clinic, assessing the intervention's impact on child health, behavior, and development and caregiver stress and mental health.

NCT ID: NCT05516108 Completed - Stress Clinical Trials

Remote Mindfulness Training Following Early Life Adversity

ReMind
Start date: September 1, 2022
Phase: Phase 1
Study type: Interventional

This study will test the feasibility of delivering smartphone-based mindfulness and coping interventions to a sample of emerging/young adults with a history of early life adversity (ELA). 80 participants with a history of ELA will be randomly assigned to complete a two-week mindfulness training intervention or matched coping control intervention, both involving 14 foundational audio-guided lessons and practice prompts randomly delivered 3x daily. At baseline, post-intervention, and one-month follow-up lab assessments, participants will complete questionnaires and provide blood samples for assessment of markers of inflammation. Data assessing subjective and physiological stress in daily life will be collected during the intervention and for one week before, immediately after, and one month after the intervention. Passive sensor data will be continuously collected from participants' smartphones and wearable devices to develop exploratory models that estimate and predict daily life stress. Data will be used to evaluate feasibility and acceptability of interventions and assessments in an ELA sample, test effects of mindfulness training on daily life stress and markers of inflammation in an ELA sample, and develop exploratory machine learning models of stress from passive sensor data.

NCT ID: NCT05259436 Recruiting - Caregiver Stress Clinical Trials

Collaborative Approach to Examining Adversity and Building Resilience Study

CARE
Start date: April 11, 2022
Phase: N/A
Study type: Interventional

To examine the behavioral, psychosocial, and biologic impact of resilience-promoting interventions associated with primary care.

NCT ID: NCT02400593 Completed - Chronic Stress Clinical Trials

Health Experiences & Early Life Disadvantages

HEELD
Start date: August 2015
Phase: N/A
Study type: Interventional

Growing up in a low-income household has been shown to increase risk for, and susceptibility to many illnesses.The purpose of the study is to test an affective intervention for reversing biological risk factors, as related to childhood adversity, in midlife. Participants will be asked to make two lab visits; attend six weekly, 1-hour meditation classes; as well as complete brief online daily surveys for 11 weeks, five biweekly surveys, and two 30-minute surveys prior to each lab visit. During the lab visits, participants will have their psychophysiology monitored for heart rate, blood pressure, respiration, and pulse. Participants will also have their blood drawn. All surveys and questionnaires inquire about participants' current demographics, family history, perceptions about life and well-being, physical health, and monetary choices.