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E-Cig Use clinical trials

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NCT ID: NCT05869318 Recruiting - E-Cig Use Clinical Trials

Respiratory Effects of E-Cigarettes in Obese Youth

RESEC
Start date: April 4, 2023
Phase: N/A
Study type: Interventional

To determine vaping behaviors and respiratory function in obese and nonobese youth e-cigarette users.

NCT ID: NCT05482581 Recruiting - E-Cig Use Clinical Trials

The Impact of Policies Regarding E-cigarette on Adolescents and Young Adults' Cognition and Behavior for E-cigarette

Start date: May 27, 2022
Phase:
Study type: Observational

Based on the Knowledge,Attitude,Belief and Practice model(KABP model), this study intends to use a mixed method to explore the influencing mechanism of youth and adolescents' cognition and behavior for e-cigarette before and after the promulgation of the new regulations on e-cigarette . Information from network epidemiology (including network links, text, images, audio, video, etc.) was captured to expand the data abundance, and the retrieval behavior of e-cigarettes and the trajectory changes of e-cigarette-related events were explored. Finally, summarize the data, integrate and explain the influencing mechanism of youth and adolescents' attention and cognition on e-cigarette, and provide ideas for subsequent e-cigarette control, as well as theoretical and practical basis for relevant departments to formulate corresponding policies.

NCT ID: NCT05432830 Recruiting - Cigarette Smoking Clinical Trials

Sex Differences in E-cig Perception: Study 1

Start date: April 30, 2024
Phase: N/A
Study type: Interventional

The primary objective is to examine the influence of sex on sensory effects, appeal, and reinforcing value of nicotine containing e-cigs in popular flavor components; sweet and cooling.

NCT ID: NCT05199480 Recruiting - E-Cig Use Clinical Trials

Understanding the Impact of Cartridge-Based Electronic Cigarettes and Generated Aerosols on Cardiopulmonary Health

Start date: January 10, 2022
Phase: Early Phase 1
Study type: Interventional

Over the last decade, e-cigarettes have become increasingly popular, due to their promotion as a healthy alternative to traditional tobacco cigarettes. However, there are large discrepancies of knowledge in understanding how these e-cigarettes affect the user's health. The overall goal of this study is to evaluate the impact of e-cigarettes usage on user's cardiopulmonary health

NCT ID: NCT04974580 Recruiting - Nicotine Dependence Clinical Trials

Research and Innovation to Stop E-cigarette/Vaping in Young Adults

(RISE)
Start date: July 5, 2021
Phase: Phase 4
Study type: Interventional

The aim of this study is to test intervention components to help young adults quit vaping. A 2x2 factorial design will be used where all participants receive quitline-delivered behavioral phone counseling, and components to be tested are a digital intervention (with text and online cessation support) and nicotine replacement therapy (NRT). The research questions and hypotheses for this study are: 1. Which components and combinations of intervention yield the greatest success rates for exclusive vaping cessation among young adult exclusive e-cigarette users? H1: The complete condition (NRT + digital) will yield significantly higher rates of cessation compared to the control condition (quitline only). 2. Does 8 weeks of nicotine replacement therapy (NRT) improve initial cessation outcomes relative to no NRT. H2: Providing NRT will yield significantly higher quit rates compared to the No NRT condition. 3. Do tailored text-messages and online support during cessation improve initial cessation outcomes relative to no digital content? Are young adult vapers engaged with and satisfied with digital cessation tools? H3: Digital support will yield significantly higher quit rates compared to no digital support. H4: Higher engagement in digital content will be associated with higher cessation success rates.

NCT ID: NCT04898075 Recruiting - E-Cig Use Clinical Trials

Quit Nicotine: E-Cig Cessation Intervention

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to find out if a new intervention helps teenagers who vape nicotine quit vaping. The program involves two parts: giving rewards (also called contingency management [CM]) and online video counseling (also called cognitive behavioral therapy [CBT]).

NCT ID: NCT04662658 Recruiting - E-Cig Use Clinical Trials

Hyperpolarized Xenon-129 MR Imaging of the Lung

e-cigarette
Start date: November 5, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Over the past 10 years, electronic cigarettes (e-cigarettes, EC) have been commercialized as a "less harmful" alternative to traditional cigarettes.1,2 However, e-cigarettes are believed to cause pulmonary epithelial, endothelial and vascular dysfunction, and to cause murine phenotypes similar to those of human COPD. Recently, "spiked" vape juice has been linked to severe lung damage. Unfortunately, the effects of e-cigarettes on the human lungs are still poorly understood, especially in healthy young adults. Therefore, establishing the health effects of e-cigarettes in humans is of paramount importance to guide medical and regulatory decision making. Its widespread use and immense popularity among teenagers and young adults have caused major concern given potentially significant addictive and detrimental long-term health effects.

NCT ID: NCT04395274 Recruiting - E Cig Use Clinical Trials

Young Adult EC Use and Respiratory Outcomes

Start date: July 15, 2021
Phase:
Study type: Observational

E-cigarette (EC) use continues to increase among youth, and EC may be detrimental to youth respiratory health. Public health officials and the Food and Drug Administration (FDA) can now regulate ECs. The proposed study uses naturalistic assessments called ecological momentary assessment (EMA) to understand how ECs use may impact the respiratory health of youth and young adult users compared to never-using peers.

NCT ID: NCT04188197 Recruiting - Smoking Cessation Clinical Trials

Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes

RECON
Start date: August 26, 2019
Phase: Phase 3
Study type: Interventional

This study will evaluate a reward devaluation strategy in which smokers use the JUUL e-cigarette immediately before any combustible cigarettes (CCs) are smoked. This procedure is predicted to accomplish three goals: 1) the rewarding effects of CC will be disrupted because subjects will already have attained fairly high peak nicotine concentrations immediately before smoking the cigarette. This reduces the rewarding effect of smoking, in part from receptor desensitization that occurs following nicotine exposure, which reduces the response to a subsequent dose of nicotine, and in part from satiating the drive to smoke; 2) the use of the JUUL will become associated with the same cues that elicit smoking, thereby promoting the substitution of JUUL use for CC use; and 3) ad libitum nicotine intake from the JUUL and its rewarding effects will be maximized because, unlike CC, they will be experienced after a period of nicotine deprivation. Thus, despite a lower per-puff nicotine dose relative to CC, the pharmacologic impact and reinforcing effect will be maximized. The study will evaluate two flavors (Mint and Virginia Tobacco), randomly assigned, to determine if flavor assignment (similar to the subjects' usual brand of CC or different than the subjects usual brand CC) has an effect on the success of this reconditioning procedure.

NCT ID: NCT04063267 Recruiting - Cigarette Smoking Clinical Trials

Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder

Start date: October 27, 2020
Phase: Phase 2
Study type: Interventional

Patients in addiction treatment have exceptionally higher rate of cigarette smoking and very low quit rates compared to the general population. The purpose of this study is to examine the feasibility of using e-cigarettes as a method for harm reduction and the effects of providing e-cigarettes (or placebo e-cigarettes) on smoking outcomes among patients in addiction treatment.