Clinical Trial Details
— Status: Active, not recruiting
Administrative data
NCT number |
NCT03351218 |
Other study ID # |
C17-04 |
Secondary ID |
2017-A01231-52 |
Status |
Active, not recruiting |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
October 23, 2017 |
Est. completion date |
October 15, 2022 |
Study information
Verified date |
November 2021 |
Source |
Institut National de la Santé Et de la Recherche Médicale, France |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
In this study, using computerized cognitive assessments combined with multi-modal
neuroimaging approach investigators aim to address three specific questions on patients with
cervical and myoclonus dystonia:
(i) investigate various aspects of the sense of agency and relationship to the severity of
dystonia symptoms, (ii) characterize the possible link between abnormalities of movement
perception and alteration of sense of agency in dystonia, (iii) (identify the neuronal
underpinnings of the defective sense of agency in dystonia.
Description:
This is a single-centre, two-group ( dystonia and control), case-control study using
behavioural and novel multimodal neuroimaging techniques to address the study aims.
The battery of the tasks will include explicit-agency tasks, a visual discrimination task on
objects movement perception. The magnetic resonance acquisition protocol will include MP2RAGE
structural (10 min duration), multi echo (3 echo times) multiband (MB factor 4) resting state
functional neuroimaging (15 minutes duration) and multi shell diffusion imaging sequence (15
minutes duration)