PAthwAy of Dyspneic patIent in Emergency in the North-east Region (North-East PArADIsE)

Dyspnea Clinical Trial

— N_E_PARADISE  

Official title:

PAthwAy of Dyspneic patIent in Emergency in the North-east Region

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06235008
• Other study ID #: 2020PI059
• Status: Not yet recruiting
• Start date: March 31, 2024
• Est. completion date: September 30, 2030

Study information

• Verified date: January 2024
• Source: Central Hospital, Nancy, France
• Contact: GIRERD Nicolas
• Phone: 0383157322
• Email: n.girerd[@]chru-nancy.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This is an observational retrospective multi-center study in patients managed for acute dyspnea by Emergency department medical team.

The main aim of the study is to evaluate factors associated with mortality risks in patients managed for acute dyspnea by an Emergency department medical team, overall, as well as in subgroups of interest (male/female, age categories, mode of admission and comorbidities).

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 75000
• Est. completion date: September 30, 2030
• Est. primary completion date: March 31, 2029
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Man or women = 18 years

• Patients with acute dyspnea cared by a medical team of the emergencies of CHRU of Nancy, CHR Metz-Thionville and CH d'Epinal.

Exclusion Criteria:

• Cardiorespiratory arrest before medical management by the Emergency Department team

• Adults under legal protection

Related Conditions & MeSH terms

• Dyspnea
• Emergencies

Locations

Country	Name	City	State
France	CHRU	Nancy

Sponsors (1)

Lead Sponsor	Collaborator
Pr. Nicolas GIRERD

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	All-cause mortality		Within 5 years following hospital discharge
Secondary	Main diagnosis during the initial hospitalization		Within hospital stay, maximum 21 days
Secondary	Mismatch between diagnosis in the Emergency department and at discharge	Difference between the diagnosis reported in the Emergency department file and the diagnosis reported at hospital discharge.	Within hospital stay, maximum 21 days
Secondary	Length of hospital stay		Within hospital stay, maximum 21 days
Secondary	Administration of non-invasive ventilation		Within hospital stay, maximum 21 days
Secondary	Timing of non-invasive ventilation		Within hospital stay, maximum 21 days
Secondary	Administration of diuretics		Within hospital stay, maximum 21 days
Secondary	Timing of diuretics		Within hospital stay, maximum 21 days
Secondary	Post emergency admission	Type of department admitting the patient following emergency care (intensive care unit, cardiology unit, cardiac intensive care unit, post-emergency department, other...)	Within hospital stay, maximum 21 days
Secondary	All-cause hospital mortality		Within hospital stay, maximum 30 days
Secondary	Readmissions (all-cause and related to acute dyspnea) to the emergency department		Within 5 years after admission
Secondary	Congestion score	Assessed by: Congestion score assessed on chest X-ray on admission to the emergency department. The congestion score ranges from 0 (indicating no congestion signs) to 3 (indicating intense congestion).	Within 2 days of admission