POCUS VS CT in Diagnosis of Acute Dyspnea in Chronic Hemodialysis Patients

Dyspnea Clinical Trial

Official title:

Predictive Value of Point of Care Ultrasound (POCUS) Versus Computerized Tomography (CT) in Diagnosis of Acute Dyspnea in Chronic Hemodialysis Patients.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05729035
• Other study ID #: POCUS VS CT chest
• Status: Not yet recruiting
• Start date: February 2023
• Est. completion date: April 2024

Study information

• Verified date: February 2023
• Source: Assiut University
• Contact: Randa Ahmed Sarhan
• Phone: 01118683728
• Email: randaahmedsarhan[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Estimate the predictive value of POCUS in diagnosis of different causes of acute dyspnea in hemodialysis patients and compare between POCUS and CT in differentiation the causes of acute dyspnea in those population.

Description:

Dyspnea is "a subjective experience of breathing discomfort that consists of qualitatively dis-tinct sensations that vary in intensity.Dyspnea is a common symptom both in general practice and in hospital emergency rooms. It has been reported that 7.4% of patients presenting to emergency rooms complain of dyspnea;among patients in general practice, 10% complain of dyspnea when walking on flat ground and 25% complain of dyspnea on more intense exertion, e.g., climbing stairs.Dyspnea is considered acute when it develops over hours to days.Acute breathlessness in haemodialysis patients can be caused by various conditions such as acute coronary syndrome, catheter-related infection, pneumonia and pericardial effusion, as well as a reaction to the dialyser or medication given during dialysis Hence, clinical acumen remains integral in evaluation of acute breathlessness in this group of patients. Point of Care Ultrasound is complementary to a medical examination performed by primary care physicians in conjunction to physical examination to investigate unclear findings. As such it is used to find and identify either the presence or absence of specific pathological results seen in your patients.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 100
• Est. completion date: April 2024
• Est. primary completion date: February 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• All patients maintained on regular hemodialysis equal to / more than 6 months admitted to emergency department and ICU of Internal Medicine Department from September 2021 to August 2022 presented by acute dyspnea.

Exclusion Criteria:

• • Age less than 18
• Diagnosed chronic pulmonary disease.
• Severe heart failure (NYHA class IV).
• Active malignancy.
• Pregnancy.
• Hepatic Failure (Child B,C).
• Comatosed Patients.

Related Conditions & MeSH terms

• Chronic Renal Failure
• Dyspnea
• Kidney Failure, Chronic

Intervention

Radiation:
• POCUS
Point of Care Ultrasound is complementary to a medical examination performed by primary care physicians

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Randa Ahmed Sarhan

References & Publications (3)

Li L, Yong RJ, Kaye AD, Urman RD. Perioperative Point of Care Ultrasound (POCUS) for Anesthesiologists: an Overview. Curr Pain Headache Rep. 2020 Mar 21;24(5):20. doi: 10.1007/s11916-020-0847-0. — View Citation

Rice JA, Brewer J, Speaks T, Choi C, Lahsaei P, Romito BT. The POCUS Consult: How Point of Care Ultrasound Helps Guide Medical Decision Making. Int J Gen Med. 2021 Dec 15;14:9789-9806. doi: 10.2147/IJGM.S339476. eCollection 2021. — View Citation

Smallwood N, Dachsel M. Point-of-care ultrasound (POCUS): unnecessary gadgetry or evidence-based medicine? Clin Med (Lond). 2018 Jun;18(3):219-224. doi: 10.7861/clinmedicine.18-3-219. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Compare between POCUS and CT in differentiation the causes of acute dyspnea in hemodialysis patients.	Predictive value of Point of Care Ultrasound (POCUS) versus computerized tomography (CT) in Diagnosis of Acute Dyspnea in Chronic Hemodialysis Patients.	All patients maintained on regular hemodialysis equal to / more than 6 months admitted to emergency department and ICU of Internal Medicine Department from September 2021 to August 2022 presented by acute dyspnea