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NCT05647655 Clinical Trial

Value of Transthoracic Ultrasonography (TTU) for Etiological Diagnosis of Acute Dyspnea: Cross Sectional Study

Dyspnea Clinical Trial

Official title:
Value of Transthoracic Ultrasonography (TTU) for Etiological Diagnosis of Acute Dyspnea: Cross Sectional Study

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05647655
Other study ID # US in Acute dyspnea
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date February 20, 2023
Est. completion date April 1, 2024

Study information
Verified date December 2022
Source Assiut University
Contact Ahmed A Elsayed, MBBCH
Phone 01126091101
Email ahmeda.abdelmoniem@hotmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Evaluating the capability and efficiency of transthoracic ultrasound in attempting to identify the etiology of acute dyspnea.

Description:

Acute dyspnea is a frequent challenge for physicians due to having multiple etiologies, leading to difficulty in establishing an accurate diagnosis. The presence of this symptom is already a predictor of increased mortality and a lot of investigations are required to differentiate between etiologies. Hence, prompt diagnosis is needed to streamline these patients' appropriate management and disposition from the ED. Transthoracic ultrasound has traditionally been used for the detection of pleural effusion and evaluation of the chest wall, but the indications have been expanded. The gold standard imaging technique for the majority of pulmonary disorders is high-resolution computed tomography (HRCT), but it has negatives which are: - hazard of ionizing radiation - high cost - being nonportable

Recruitment information / eligibility
Status Recruiting
Enrollment 143
Est. completion date April 1, 2024
Est. primary completion date March 1, 2024
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Clinical history of acute dyspnea Exclusion Criteria: - Subcutaneous emphysema. - Patients with more than 24 h interval between HRCT and TTU. - Patients with poor-quality of TTU image.

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Ultrasonography
Bedside thoracic ultrasound for patients complaining of acute dyspnea.

Locations
Country Name City State
Egypt Assiut University hospital Assiut

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

References & Publications (5)

Baid H, Vempalli N, Kumar S, Arora P, Walia R, Chauhan U, Shukla K, Verma A, Chawang H, Agarwal D. Point of care ultrasound as initial diagnostic tool in acute dyspnea patients in the emergency department of a tertiary care center: diagnostic accuracy study. Int J Emerg Med. 2022 Jun 13;15(1):27. doi: 10.1186/s12245-022-00430-8. — View Citation

Gargani L, Fontana M, Sicari R, Picano E. [Differential diagnosis of dyspnea: the incremental value of lung ultrasound]. Recenti Prog Med. 2010 Feb;101(2):78-82. Italian. — View Citation

Lancellotti P, Price S, Edvardsen T, Cosyns B, Neskovic AN, Dulgheru R, Flachskampf FA, Hassager C, Pasquet A, Gargani L, Galderisi M, Cardim N, Haugaa KH, Ancion A, Zamorano JL, Donal E, Bueno H, Habib G. The use of echocardiography in acute cardiovascular care: recommendations of the European Association of Cardiovascular Imaging and the Acute Cardiovascular Care Association. Eur Heart J Cardiovasc Imaging. 2015 Feb;16(2):119-46. doi: 10.1093/ehjci/jeu210. Epub 2014 Nov 6. — View Citation

Li H, Li YD, Zhu WW, Sun LL, Ye XG, Kong LY, Cai QZ, Jiang W, Wang L, Lu XZ. High-Resolution Transthoracic Ultrasonography for Assessment of Pleural Lines in Patients With Dyspnea With CT Comparison: An Observational Study. J Ultrasound Med. 2017 Apr;36(4):707-716. doi: 10.7863/ultra.16.04030. Epub 2017 Jan 27. — View Citation

Vitturi N, Soattin M, Allemand E, Simoni F, Realdi G. Thoracic ultrasonography: A new method for the work-up of patients with dyspnea(). J Ultrasound. 2011 Sep;14(3):147-51. doi: 10.1016/j.jus.2011.06.009. Epub 2011 Jun 30. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Differentiate between different etiologies of acute dyspnea Analysis of ultrasound findings to differentiate between etiologies of acute dyspnea. Baseline
Secondary Detect value of transthoracic ultrasound (TTU) in comparison to CT chest. Comparison between accuracy of TTU and CT Baseline
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