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Dyspnea; Cardiac clinical trials

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NCT ID: NCT04886128 Active, not recruiting - Dyspnea Clinical Trials

Improving Diagnostic Accuracy for Acute Heart Failure

INDICATE-HF
Start date: August 31, 2021
Phase:
Study type: Observational

Acute heart failure is a common reason for emergency department visits and hospitalization, but the diagnosis can be challenging because of non-specific symptoms and signs. The current diagnostic approach to acute heart failure has modest accuracy, leading to delayed diagnosis and treatment, which associate with worse prognosis. Prior work suggests diagnostic accuracy can be improved with the addition of multiple circulating biomarkers discovered through proteomics, and this study will derive and validate a multi-marker model to improve diagnostic accuracy for acute heart failure in the emergency department.