Multifunctional Nutrition Tube in Dysphagia for Nasopharyngeal Carcinoma

Status Not yet recruiting

Clinical Trial Summary

Baseline information (demographics, medical history, etc.), nutritional status at admission and after treatment, depression, dysphagia, and quality of life (QOL) after treatment as well as adverse events are compared. Palliation to delayed dysphagia after radiotherapy for nasopharyngeal carcinoma (NPC) continues to be a challenge. Although nasogastric tube feeding (NGT) has been adopted widely, the weaknesses have yet to be improved by another enteral nutrition support mode. This study aims to observe the clinical efficacy of intermittent oro-esophageal tube feeding (IOE) in the treatment of delayed dysphagia after radiotherapy for (NPC). This is a prospective multicenter study with patients with delayed dysphagia after radiotherapy for NPC. Patients enrolled are randomly divided equally into the observation group and the control group. All patients receive conventional care, and the observation group received IOE while the control group received NGT for enteral nutrition support.

Clinical Trial Description

Palliation to delayed dysphagia after radiotherapy for nasopharyngeal carcinoma (NPC) continues to be a challenge. Although nasogastric tube feeding (NGT) has been adopted widely, the weaknesses have yet to be improved by another enteral nutrition support mode. This study aims to observe the clinical efficacy of intermittent oro-esophageal tube feeding (IOE) in the treatment of delayed dysphagia after radiotherapy for (NPC). This is a prospective multicenter study with patients with delayed dysphagia after radiotherapy for NPC. Patients enrolled are randomly divided equally into the observation group and the control group. All patients receive conventional care, and the observation group received IOE while the control group received NGT for enteral nutrition support. Baseline information (demographics, medical history, etc.), nutritional status at admission and after treatment, depression, dysphagia, and quality of life (QOL) after treatment as well as adverse events are compared. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06328868
Study type	Interventional
Source	Chao Phya Abhaibhubejhr Hospital
Contact	Lavie Ce
Phone	15333866454
Email	zengxizdyfy@126.com
Status	Not yet recruiting
Phase	N/A
Start date	March 2024
Completion date	December 2024

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT03711474` - Dysphagia Following Anterior Cervical Spine Surgery; Single Dose Steroid vs Saline (DysDexVSSal)	Phase 4
Enrolling by invitation	`NCT04074356` - Non-invasive Markers of Esophageal Function in Adults	N/A
Suspended	`NCT04349462` - Post Critical Illness Dysphagia in the Intensive Care Unit	N/A
Not yet recruiting	`NCT05982977` - Study on the Effect Mechanism of Acupuncture Combined With Swallowing Training in Oral Dysphagia of Stroke	N/A
Recruiting	`NCT03605381` - MORbidity PRevalence Estimate In StrokE
Active, not recruiting	`NCT03455608` - PRO-ACTIVE: Prophylactic Swallow Intervention for Patients Receiving Radiotherapy for Head and Neck Cancer	N/A
Active, not recruiting	`NCT03604822` - Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS	N/A
Recruiting	`NCT03682081` - Interventions for Patients With Alzheimer's Disease and Dysphagia	N/A
Completed	`NCT05700838` - Refining Cough Skill Training in Parkinson's Disease and Dysphagia	Phase 1
Not yet recruiting	`NCT04064333` - Slow-Stream Expiratory Muscle Strength Training for Veterans With Dysphagia Living in Long-term Care	N/A
Completed	`NCT02927691` - Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial	Phase 2
Not yet recruiting	`NCT02724761` - Prophylactic Racemic Epinephrine in Anterior Cervical Discectomy and Fusion	N/A
Completed	`NCT01919112` - Fostering Eating After Stroke With Transcranial Direct Current Stimulation	N/A
Completed	`NCT01370083` - Tongue Pressure Profile Training for Dysphagia Post Stroke	Phase 2
Completed	`NCT01723358` - Neuromuscular Electrical Stimulation (NMES) Treatment Technique Therapy in the Management of Young Infants With Severe Dysphagia	Phase 2
Withdrawn	`NCT01200147` - Effectiveness of Rupture of Schatzki's Ring Using Biopsy Forceps Versus SIngle Dilation	N/A
Completed	`NCT00570557` - Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia	N/A
Recruiting	`NCT00166751` - Sonographic Assessment of Laryngeal Elevation	N/A
Completed	`NCT00717028` - Functional Endoscopic Evaluation of Swallowing	N/A
Completed	`NCT01476241` - Percutaneous Endoscopic Gastrostomy Tube Placement by Otorhinolaryngologist	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.