Dysmenorrhea Clinical Trial
Official title:
Efficacy and Safety of Intravenous Tramadol Versus Intravenous Paracetamol for Relief of Acute Pain of Primary Dysmenorrhea: A Randomized Controlled Trial
Verified date | June 2020 |
Source | Cairo University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Patients presented with primary dysmenorrhea composed the study population. One gram paracetamol and 100 mg tramadol in 100 ml saline with a slow infusion were compared in ceasing dysmenorrhea in the emergency department
Status | Completed |
Enrollment | 100 |
Est. completion date | October 20, 2018 |
Est. primary completion date | October 1, 2018 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: - Patients with moderate to severe primary dysmenorrhea and visual analog scale (VAS) pain scores =40 - Patients over 18 years old Exclusion Criteria: - denied to give inform consent, irregular menstrual cycles, known or suspected secondary dysmenorrhea - Renal or liver failure - Allergy to the study drugs - Receiving pain killer within the last 6 hours. - Physical examination findings consistent with peritoneal irritation - Pregnancy or patients with lactation - Drug or Alcohol Abuse |
Country | Name | City | State |
---|---|---|---|
Egypt | Aljazeerah Hospital | Giza |
Lead Sponsor | Collaborator |
---|---|
Cairo University | Algazeerah hospital |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | acute pain of dysmenorrhea measured by visual analogue scale | Change in visual analogue scale at 15th minutes from baseline | 15 minutes | |
Primary | pain of dysmenorrhea measured by visual analogue scale | Change in visual analogue scale at 30th minutes from baseline | 30 minutes | |
Primary | pain of dysmenorrhea measured by visual analogue scale | Change in visual analogue scale at 60th minutes from baseline | 60 minutes | |
Secondary | Rescue drug need | the need for additional analgesic drug | 30 minutes. | |
Secondary | adverse effects. | nausea, Vomiting, epigastric pain | 60 minutes |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04607382 -
Survey on Menstrual Symptoms, Health Related Quality of Life and Work Productivity in Patients Suffering From Pain During Menstruation (Dysmenorrhea) in Japan
|
||
Recruiting |
NCT04091789 -
Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea
|
Phase 2 | |
Completed |
NCT00746096 -
Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Primary Dysmenorrhea
|
Phase 3 | |
Completed |
NCT00769964 -
VA111913 TS: First in Human Study
|
Phase 1 | |
Completed |
NCT00104546 -
Vitamin K Injections for the Treatment of Painful Menstruation
|
Phase 1 | |
Completed |
NCT06011928 -
MOPEXE and RE in Treating Dysmenorrhea
|
N/A | |
Not yet recruiting |
NCT06398990 -
The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With Dysmenorrhoea
|
N/A | |
Recruiting |
NCT02031523 -
Multi-center Clinical Trials of Sanjie Analgesic Capsule in Treating Endometriosis
|
Phase 4 | |
Completed |
NCT01449305 -
Effectiveness of Nanoone Woman Underwear Using in the Management of Dysmenorrhea
|
N/A | |
Completed |
NCT00995917 -
A Pilot Study of Acupoint Injection for Primary Dysmenorrhea
|
N/A | |
Completed |
NCT02910167 -
Observational Prospective Study to Evaluate AEs, Risk Factors and Drug Utilization of BUSCAPINA COMPOSITUM N in Adults From Metropolitan Lima
|
||
Not yet recruiting |
NCT05461846 -
Effect of Integrated Neuromuscular Inhibition Technique in Females With Menstrual Low Back Pain
|
N/A | |
Completed |
NCT05247333 -
Implementation of a Minor Ailment Service in Community Pharmacy Practice
|
N/A | |
Not yet recruiting |
NCT03697746 -
Comparison of Dexketoprofen, Paracetamol and Ibuprofen in the Treatment of Primary Dysmenorrhea
|
N/A | |
Recruiting |
NCT03394547 -
Pulsed Electromagnetic Field Treatment for Painful Periods
|
N/A | |
Recruiting |
NCT06294743 -
Posterior Tibia Nerve Neuroprolotherapy for Dysmenorrhea
|
Early Phase 1 | |
Active, not recruiting |
NCT01738204 -
The Women's Health Study: From Adolescence to Adulthood
|
||
Completed |
NCT01462370 -
Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-0663-145 AM1)
|
Phase 3 | |
Completed |
NCT01250587 -
Dose-Finding Study of PDC31 in Patients With Primary Dysmenorrhea
|
Phase 1 | |
Completed |
NCT00951561 -
A Comparison Study of Pain Relief From Dysmenorrhea Between the Vipon Tampon and Ibuprofen
|
N/A |