Dysmenorrhea Clinical Trial
Official title:
The Efficacy of Viburnum Opulus 3X in the Treatment of Primary Dysmenorrhea
Dysmenorrhea (painful menstruation) is a common gynaecological disorder that is prevalent in
more than 50% of women during their reproductive years. Primary dysmenorrhea describes
cyclic uterine pain without any identifiable or underlying causes. Menstrual pain results as
a consequence of endometrial ischemia, high levels of prostaglandins and other inflammatory
mediators. Conventional treatment for primary dysmenorrhea consists of non-steroidal
anti-inflammatory drugs and oral contraceptives, which may have adverse effects. Viburnum
opulus (Cramp bark) is a homoeopathic remedy well indicated for the treatment of
dysmenorrhea. While there are studies using Viburnum opulus in its herbal form, there is no
research assessing its efficacy in the homoeopathic form.
The aim of this study is to determine the efficacy of Viburnum opulus 3X in the treatment of
primary dysmenorrhea as measured with the modified Short Form McGill pain questionnaire
(SF-MPQ-2) and visual analogue scale (VAS) respectively.
Status | Completed |
Enrollment | 30 |
Est. completion date | December 2015 |
Est. primary completion date | December 2015 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 35 Years |
Eligibility |
Inclusion Criteria: - Females between 18-35 years. - Have a history of painful menstruation. Exclusion Criteria: - Are on any form of hormonal contraceptives. - Have intra uterine contraceptive devices. - Have prediagnosed endometriosis, chronic pelvic inflammatory disease, uterine fibroids, polycystic ovarian syndrome or other known causes of secondary dysmenorrhea. - Suffers from any serious chronic disease. |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
South Africa | University of Johannesburg | Johannesburg | Gauteng |
Lead Sponsor | Collaborator |
---|---|
University of Johannesburg |
South Africa,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Pain as measured by the Short Form McGill Pain Questionnaire (SF-MPQ-2) | The SF-MPQ-2 is a highly reliable and sensitive instrument used to asses and measure pain levels. | 3 months | No |
Secondary | Pain as measured by the Visual Analogue Scale (VAS) | The scale (VAS) is a validated and established tool used clinically to assess pain levels. | 3 months | No |
Secondary | Patient satisfaction as measured by the 5-Point Treatment Satisfaction Scale | The 5-Point Treatment Satisfaction Scale is a reliable tool to assess patient satisfaction with the treatment provided. This will be conducted once at the final consultation. | 1 day | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04607382 -
Survey on Menstrual Symptoms, Health Related Quality of Life and Work Productivity in Patients Suffering From Pain During Menstruation (Dysmenorrhea) in Japan
|
||
Recruiting |
NCT04091789 -
Sublingual Tablets With Cannabinoid Combinations for the Treatment of Dysmenorrhea
|
Phase 2 | |
Completed |
NCT00746096 -
Efficacy and Safety Study of Low Dose Oral Contraceptive Pill to Treat Primary Dysmenorrhea
|
Phase 3 | |
Completed |
NCT00769964 -
VA111913 TS: First in Human Study
|
Phase 1 | |
Completed |
NCT00104546 -
Vitamin K Injections for the Treatment of Painful Menstruation
|
Phase 1 | |
Completed |
NCT06011928 -
MOPEXE and RE in Treating Dysmenorrhea
|
N/A | |
Not yet recruiting |
NCT06398990 -
The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With Dysmenorrhoea
|
N/A | |
Recruiting |
NCT02031523 -
Multi-center Clinical Trials of Sanjie Analgesic Capsule in Treating Endometriosis
|
Phase 4 | |
Completed |
NCT01449305 -
Effectiveness of Nanoone Woman Underwear Using in the Management of Dysmenorrhea
|
N/A | |
Completed |
NCT00995917 -
A Pilot Study of Acupoint Injection for Primary Dysmenorrhea
|
N/A | |
Completed |
NCT02910167 -
Observational Prospective Study to Evaluate AEs, Risk Factors and Drug Utilization of BUSCAPINA COMPOSITUM N in Adults From Metropolitan Lima
|
||
Not yet recruiting |
NCT05461846 -
Effect of Integrated Neuromuscular Inhibition Technique in Females With Menstrual Low Back Pain
|
N/A | |
Completed |
NCT05247333 -
Implementation of a Minor Ailment Service in Community Pharmacy Practice
|
N/A | |
Not yet recruiting |
NCT03697746 -
Comparison of Dexketoprofen, Paracetamol and Ibuprofen in the Treatment of Primary Dysmenorrhea
|
N/A | |
Recruiting |
NCT03394547 -
Pulsed Electromagnetic Field Treatment for Painful Periods
|
N/A | |
Recruiting |
NCT06294743 -
Posterior Tibia Nerve Neuroprolotherapy for Dysmenorrhea
|
Early Phase 1 | |
Active, not recruiting |
NCT01738204 -
The Women's Health Study: From Adolescence to Adulthood
|
||
Completed |
NCT01462370 -
Study to Assess the Safety and Efficacy of Etoricoxib Versus Ibuprofen in the Treatment of Dysmenorrhea (MK-0663-145 AM1)
|
Phase 3 | |
Completed |
NCT01250587 -
Dose-Finding Study of PDC31 in Patients With Primary Dysmenorrhea
|
Phase 1 | |
Completed |
NCT00951561 -
A Comparison Study of Pain Relief From Dysmenorrhea Between the Vipon Tampon and Ibuprofen
|
N/A |