Dyslipidemia Clinical Trial
Official title:
An Open-Label, Definitive Bioequivalence Study to Compare the Pharmacokinetics of the Simvastatin, Nicotinic Acid, and MK0524 (Laropiprant) Components of a Formulation of MK0524B With That of Zocor™ and MK0524A Tablets
This study will evaluate:
1. the bioequivalence of simvastatin and simvastatin acid following dose of simvastatin
(ZOCOR™) given together with one tablet of MK0524A or as a component of the triple
combination tablet MK0524B.
2. the bioequivalence of laropiprant and ER niacin when administered as the triple
combination tablet MK0524B or as the double combination tablet MK0524A given together
with simvastatin.
n/a
Allocation: Randomized, Endpoint Classification: Bio-equivalence Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment
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