Study of Hierarchy of Afferents in Postural Control of Children With Dyslexia

Dyslexia Clinical Trial

— EQUIDYS  

Official title:

Study of Hierarchy of Afferents in Postural Control of Children With Dyslexia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02879786
• Other study ID #: 2011-A00139-32
• Status: Completed
• Phase: N/A
• First received: August 23, 2016
• Last updated: August 23, 2016
• Start date: July 2011
• Est. completion date: June 2015

Study information

• Verified date: August 2016
• Source: Central Hospital, Nancy, France
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Agence Nationale de Sécurité du Médicament et des produits de santé
• Study type: Interventional

Clinical Trial Summary

The purpose is to determine the hierarchy of sensory afferents according to different forms of dyslexia in children.

The secondary purpose is to determine sensitive and sufficiently specific posturographic indexes for standard diagnosis of different types of dyslexia.

Description:

This study evaluates the postural control and the importance of proprioception, evaluated by static and dynamic posturography, in dyslexic children compared to age-matched control group. Posturographic data and a questionnaire for motion sickness disorder are used as proprioceptive disorder index. This study aims to better characterize the dyslexic population with techniques targeting central integration of sensory proprioceptive afferents. The purpose of this study is not to search for a postural deficiency syndrome, but to study proprioception with posturography, with quantitative and normalized data of analyzed population. Moreover, these data could allow an objective evaluation of reeducation with quantifiable and reproducible parameters in order to judge its effectiveness. The demonstration of the existence of a relationship between proprioceptive disorders and dyslexia will imply a specific reeducation care of patients. A study using validated and standard indexes is necessary. The presence of postural disorders and a major susceptibility to motion sickness could contribute to distinguish different forms of dyslexia and thus be complementary to actual medical, orthophonic and neuropsychological criteria. In this evaluation, it is important to distinguish between visuo-attentional dyslexia from phonological dyslexia involving distinct anatomo-functional neuronal circuits.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 68
• Est. completion date: June 2015
• Est. primary completion date: June 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 8 Years to 13 Years

Eligibility

Inclusion Criteria:

All:

• Parents of child and child having given informed consent

• Affiliation to social security

• Preliminary medical examination

Dyslexia groups:

• Diagnosed and characterized dyslexia

Exclusion Criteria:

All:

• Medical pathology, especially neurological, ophthalmological, otorhinolaryngological or orthopedic, modifying postural control, detected with medical examination

• Insufficient compliance of child especially due to fatigue

• Contact allergy to cutaneous electrodes

• Current treatments: psychotropic drugs and all drugs diminishing awareness or causing dizziness or equilibrium disorders

Control group:

• Patient having a dyslexia or oral or written language disorder

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Dyslexia

Intervention

Other:
• Posturographic tests

• Questionnaire of motion sickness susceptibility

Locations

Country	Name	City	State
France	Centre de Référence pour les Troubles des Apprentissages - Hôpital d'Enfants - CHU de Nancy	Vandoeuvre lès Nancy

Sponsors (1)

Lead Sponsor	Collaborator
Central Hospital, Nancy, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Score of evaluation of motion sickness susceptibility		day 0	No
Primary	Score of equilibrium evaluated with posturographic test		day 0	No