Dyslexia Clinical Trial
Official title:
Computerized Working Memory Training for Children With Dyslexia
The main aim of this interventional study is to investigate whether the effects of computerized working memory training improves reading abilities for children, i.e. ages 9 - 16 years, diagnosed with dyslexia.
Dyslexia is a specific learning difficulty which mainly affects the development of literacy
and language related skills. It is characterized by difficulties with phonological
processing, rapid naming, working memory, processing speed and the automatic development of
skills that may not match up to an individual's other cognitive abilities. Phonological
processing deficit is well established as one of the main causes of dyslexia. Working memory
(WM) is today considered to be a cognitive system that strongly relates to a person's
ability to think and learn. Over the last decade an increasing body of evidence indicates
that WM deficits may cause particular problems for individuals with dyslexia. This is
consistent with many of the every day problems reported by dyslexics and those around them.
WM deficits are frequent in children with reading deficits. A major question is whether the
WM impairment is secondary to phonological core deficit affecting the phonological loop
only, or caused by an additional deficit involving central executive. Exploratory findings
from fMRI studies indicates that impaired WM processes in dyslexia have a unique neuronal
signature which may be associated with central executive processes. However there are
conflicting findings and further studies are needed.
The children in the study, all diagnosed with dyslexia, will be divided into two subgroups
(16/16 children). They are randomly allocated to either the adaptive training group or the
treatment as usual control group after the baseline assessment. Both groups will meet for
baseline testing and re-testing 4 weeks after completed training. Those that serve as
non-trained controls will be offered to participate in training after completion of the
study.
The intervention in this study aim to increase WM of children with dyslexia. We hypothesise
that intensive computerized working memory training will improve reading fluency, speed and
comprehension for children with dyslexia.
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Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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