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Dwarfism, Pituitary clinical trials

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NCT ID: NCT00778518 Completed - Clinical trials for Growth Hormone Deficiency

Safety, Tolerability and PK/PD Study in Young Adult Patients With Childhood Onset Growth Hormone Deficiency (GHD).

Start date: July 2008
Phase: Phase 2
Study type: Interventional

Study to find the optimal dose of Growth Hormone Replacement in young adult patients suffering from childhood onset growth hormone deficiency (GHD).

NCT ID: NCT00738205 Completed - Clinical trials for Chronic Renal Failure

Evaluation of Convenience and Compliance of the Easypod™ Electronic Self-injector

Start date: June 2007
Phase: N/A
Study type: Observational

This is an international, multicenter study involving children treated with Saizen®, a growth hormone, who will be trained to use easypod, a new electronic injector and will complete a questionnaire after 12 week of use. Both children naïve to growth hormone and dissatisfied with their current injection device will be recruited.

NCT ID: NCT00715689 Completed - Clinical trials for Adult Growth Hormone Deficiency

Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083

Start date: July 2008
Phase: Phase 2
Study type: Interventional

This trial is conducted in Europe. The aim of this clinical trial is to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of NNC126-0083 in growth hormone deficient adults

NCT ID: NCT00711061 Completed - Clinical trials for Growth Hormone Deficiency

Cardiovascular Risk in Growth Hormone Deficient Young Adult Males After Completing Growth Hormone Therapy

Start date: June 2008
Phase: N/A
Study type: Observational

The purpose of this study is to compare the cardiovascular risks of growth hormone deficient young adult males who have completed growth hormone therapy to healthy young adult males.

NCT ID: NCT00689260 Completed - Clinical trials for Growth Hormone Deficiency

Easypod United States User Trial

Start date: March 2008
Phase: Phase 4
Study type: Interventional

This study will help to determine whether an injection log on a recombinant human growth hormone (rhGH) delivery device improves subjects' adherence with injection schedules. Adherence will be compared between a group of subjects who are aware of the injection log on the easypod™ rhGH delivery device and a group of subjects who are not aware of the easypod™ injection log. It is the study hypothesis that subject non-adherence rate is different for those who are aware of the injection log capability versus those who are unaware of the injection log capability. Subject perception will also be evaluated by comparing the ease and convenience of use and subject preference for the easypod™ compared to two other rhGH pen injection devices.

NCT ID: NCT00675506 Completed - Clinical trials for Growth Hormone Deficiency

Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are Obese

Start date: July 2008
Phase: Phase 2
Study type: Interventional

Obesity, a condition that occurs when a person has too much body fat, affects about 31% of people in the United States. It is associated with increased risk of diabetes, high blood pressure, high cholesterol, and cardiovascular disease. Abdominal obesity, in particular, is also associated with low levels of growth hormone, a hormone that affects rate of growth and the way the body uses energy. Growth hormone releasing hormone (GHRH) is a substance that makes the body naturally increase its own growth hormone levels. Administering GHRH to people who are obese may help return their growth hormone levels to normal and, in turn, may lead to reduced abdominal fat and improved cardiovascular function. This study will evaluate the effectiveness of synthetic GHRH in decreasing the amount of abdominal fat and improving cardiovascular function in people who are obese.

NCT ID: NCT00646815 Completed - Clinical trials for Growth Hormone Deficiency

Insulin Sensitivity and Substrate Metabolism Before and After Treatment in Patients With Growth Hormone Deficiency

Start date: March 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to further characterize the treatment related changes in insulin sensitivity, substrate metabolism and intrahepatic-intramyocellular lipids in patients with growth hormone deficiency (GHD).

NCT ID: NCT00616278 Completed - Clinical trials for Growth Hormone Deficiency

National Cooperative Growth Study in CKD

NCGS
Start date: October 2005
Phase: N/A
Study type: Observational

The purpose of this study is to learn whether growth hormone being administered to children with Chronic Kidney Disease is effective and if it has any side effects.

NCT ID: NCT00601419 Completed - Clinical trials for Dwarfism, Growth Hormone Deficiency

Drug Use Investigation of Somatropin for GHD-ADULTS.

Start date: March 2007
Phase: N/A
Study type: Observational

Post marketing drug use investigation of Genotropin for GHD-ADULTS.

NCT ID: NCT00600808 Completed - Clinical trials for Growth Hormone Deficiency

Sustained Release Formulation of Somatropin (rDNA Origin)for Injection

Start date: June 2003
Phase: Phase 2/Phase 3
Study type: Interventional

Annualised height velocity after 12/24 months treatment and HV SDS height velocity after 12/24 months treatment expressed as number of standard deviations difference from the mean population height velocity for the appropriate gender and chronological age.