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NCT ID: NCT05120622 Withdrawn - Bladder Cancer Clinical Trials

Trial of Local Cystoscopic Injection of Tremelimumab Plus Systemic Durvalumab for High Risk Non-Muscle Invasive Bladder Cancer

Rideau
Start date: September 1, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

We will conduct a Phase I trial testing whether local cystoscopic injection of tremelimumab into the bladder wall in combination with systemic administration of durvalumab in localized bladder cancer will stimulate an effective anti-tumour immune response with minimal systemic immune response and clinical toxicity.