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Duodenal Polyps clinical trials

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NCT ID: NCT00808743 Completed - Clinical trials for Familial Adenomatous Polyposis

Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis

PreDuoFAP
Start date: May 2009
Phase: Phase 2/Phase 3
Study type: Interventional

Duodenal carcinomas are the leading cause of mortality in patients with Familial Adenomatous Polyposis (FAP) who underwent prophylactic colorectal surgery. The purpose of this study is to determine wether celecoxib combined with ursodeoxycholic acid is an effective chemoprevention strategy to influence the progression of duodenal adenomas to carcinomas in patients with FAP.