Comparison of Immunization Quality Improvement Dissemination Study

Status Completed

Clinical Trial Summary

Dissemination research examines the processes and factors that lead to widespread use of evidence-based interventions. There are several theories on how to best minimize the perceived and actual burdens on practitioners associated with implementing evidence-based medicine. For instance, the pay for performance model attempts to improve physician compliance with quality guidelines by providing financial incentives. Recent studies suggest pay for performance is effective in improving practitioner performance, but it is unclear whether the gains are sustainable once incentives are stopped.

Another approach to promoting best practices is the Model for Improvement whose main method is to employ Plan-Do-Study-Act (PDSA) cycles of small changes Although this approach has been successful within individual institutions, there is minimal evidence of its effect when employed simultaneously in multiple autonomous institutions. There is also little evidence of the sustainability of outcomes after intervention activities end.

The specific aims of the proposed study are to examine the effect of quality improvement dissemination models on the immunization coverage of children ages 3 to 18 months old. The investigators propose to:

1. Determine the effect on immunization compliance of two different models of dissemination which will provide physicians 12 months of quality improvement (QI) activity support for implementing CDC immunization best practices.

Hypothesis 1a: Study participants receiving the QI technical support intervention (QITS) will have more improvement in immunization rates from baseline to immediately after support ends than participants receiving the pay for performance intervention (P4P).

Hypothesis 1b: Study participants receiving QITS will increase immunization coverage for their practices over baseline.

Hypothesis 1c: Study participants receiving P4P will increase immunization coverage for their practices over baseline.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Health Services Research

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02432430
Study type	Interventional
Source	Children's Research Institute
Contact
Status	Completed
Phase	N/A
Start date	June 2013
Completion date	June 2014

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02526394` - Pertussis and Meningitis C Concomitant Vaccination in Adolescents	Phase 4
Completed	`NCT01707212` - Prenatal Education About Infant Immunization Pain Management	Phase 3
Completed	`NCT01463176` - Music Therapy as Procedural Support for Young Children Undergoing Immunizations	N/A
Completed	`NCT01193335` - Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Preterm Compared to Term Infants.	Phase 4
Completed	`NCT04222595` - FluPRINT Study: Characterisation of the Immune and Transcriptional Response to LAIV	N/A
Completed	`NCT05794113` - Comparing the Use of a Mobile App for Surveillance of Adverse Events Following Influenza Immunization to a Web-Based Platform	N/A
Recruiting	`NCT01713322` - Testing Educational Materials in a Paediatric Setting	Phase 3
Not yet recruiting	`NCT03705455` - Immunization Schedule Alert Platform	N/A
Recruiting	`NCT01601197` - A Study of Two Injection Techniques to Reduce Pain in Infants Undergoing Immunization	Phase 3
Completed	`NCT01296906` - Population Versus Practice-based Interventions to Increase Immunizations	N/A
Completed	`NCT01399814` - Restricted Intravenous Fluid Regime Effects on Immunological Indicators of Elderly Patients Operated for Abdominal Cancer	Phase 3
Completed	`NCT01390363` - Study of Adolescent Immunization Recall Systems	N/A
Completed	`NCT02609035` - Immunization Services Model for Adult Rate Improvement	N/A
Recruiting	`NCT02200276` - Influenza Immunization in Adults Over Age 75	N/A
Completed	`NCT01677702` - Study of Yili Lactoferrin ShuHua Milk in the Improvement of Human Immunization	N/A
Recruiting	`NCT05213000` - Adjuvant Effect of Physical Exercise on Immune Response to COVID-19 Vaccination and Interactions With Stress	N/A
Completed	`NCT03188692` - Safety and Efficacy of BK1310 Intramuscular Injection in Healthy Infants	Phase 3
Completed	`NCT01379846` - Study of TAK-816 in Healthy Infants	Phase 3
Active, not recruiting	`NCT03943875` - GARDASIL 9: 3 Dose vs. 2 Dose With Delayed 3rd Dose	Phase 4
Completed	`NCT02819895` - PRIMM Trial (Phone Reminder for IMMunization)	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Comparison of Immunization Quality Improvement Dissemination Study — CIzQIDS

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms