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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT02678104
Other study ID # FRP/2016/23
Secondary ID
Status Recruiting
Phase Phase 2
First received January 24, 2016
Last updated March 13, 2017
Start date October 2016
Est. completion date August 2017

Study information

Verified date March 2017
Source Riyadh Colleges of Dentistry and Pharmacy
Contact Hezekiah A Mosadomi, Professor
Phone 00966509995087
Email prof.mosadomi@riyadh.edu.sa
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

A prospective randomized parallel trial will be carried out on 100 patients who have extraction of single molar tooth. Teeth extractions will be done under local anesthesia. The patients will be divided randomly into two parallel groups. Group 1: The patients will start using Chlorhexidine mouthwash on the second day of extraction twice daily for 7 days. Group 2: After extraction, Manuka Honey will be applied topically into the extraction socket. Postoperative instructions will be given for all patients in addition to the prescription of ibuprofen 600 mg every 8 hours for 3 days.

Re-evaluation:

Postoperative day 3: tenderness with probing the socket, empty socket, food debris, halitosis and assessment of pain. For group 2, the intra-alveolar application of honey will be repeated. Re-evaluation will be repeated in the seventh post-operative day. Acute alveolar osteitis, (dry socket) is diagnosed if the patient presented between the 2nd and 4th days with pain or tenderness in the socket with probing, empty socket and food debris with or without halitosis.


Description:

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Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
Tooth extraction
Tooth removal
Drug:
Chlorhexidine mouth wash
Chlorhexidine mouth wash
Intra-alveolar application of Manuka Honey
Intra-alveolar application of Manuka Honey directly after extraction.

Locations

Country Name City State
Saudi Arabia RiyadH Colleges of dentistry and Pharmacy Riyadh

Sponsors (1)

Lead Sponsor Collaborator
Riyadh Colleges of Dentistry and Pharmacy

Country where clinical trial is conducted

Saudi Arabia, 

References & Publications (10)

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Outcome

Type Measure Description Time frame Safety issue
Primary Pain day 3 Assessment of pain by (VAS) from (0, 1, 2,….10). on the 3rd day
Secondary Empty socket day 3 By inspection. The socket is empty and does not contain blood clot on the 3rd day
Secondary Empty socket day 7 By inspection. The socket is empty and does not contain blood clot in the 7th day
Secondary Tenderness within the socket day 3 By probing the socket on the 3rd day
Secondary Tenderness within the socket day 7 By probing the socket on the 7th day
Secondary Pain day 7 Assessment of pain by (VAS) from (0, 1, 2,….10). on the 7th day
See also
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