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Dry Mouth clinical trials

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NCT ID: NCT04189081 Completed - Dry Mouth Clinical Trials

Improvement of Dry Mouth Sufferers After Using an Experimental Dry Mouth Rinse Compared to a Water Control

Start date: May 13, 2020
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate dry mouth relief in subjects with self-reported feeling of dry mouth after using an experimental mouth rinse or a positive control compared to a water control.

NCT ID: NCT04152642 Completed - Dry Mouth Clinical Trials

A Pilot Study to Assess Dry Mouth Relief After Using an Experimental Mouth Rinse

Start date: November 4, 2019
Phase: N/A
Study type: Interventional

The objective of this pilot study is to determine if an experimental mouth rinse and a marketed dry mouth rinse are more effective in relieving dry mouth compared to water.

NCT ID: NCT03876197 Enrolling by invitation - Radiation Toxicity Clinical Trials

Mesenchymal Stem Cells for Radiation-induced Xerostomia

Start date: August 1, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

A prospective study for long-term follow-up (LTFU) to evaluate safety and efficacy in subjects who participated in the Phase 1/2 randomized placebo-controlled trial MESRIX.

NCT ID: NCT03874572 Active, not recruiting - Xerostomia Clinical Trials

Allogeneic Mesenchymal Stem Cells for Radiation-induced Hyposalivation and Xerostomia/Dry Mouth

MESRIX-SAFETY
Start date: March 18, 2019
Phase: Phase 1
Study type: Interventional

An investigator-initiated, non-randomized, open label study to investigate the safety, feasibility and tolerability of intraglandular injection of allogeneic mesenchymal stem/stromal cells (MSCs) into the submandibular and parotid glands of the patients with radiation-induced hyposalivation and xerostomia after radiation for a oropharyngeal squamous cell carcinoma

NCT ID: NCT03663231 Completed - Dry Mouth Clinical Trials

Duration of Effect of Biotene Spray in Patients With Dry Mouth

Start date: February 11, 2019
Phase: N/A
Study type: Interventional

To determine the duration of effect of a single dose of Biotène Moisturizing Mouth Spray in subjects who complain of a clinically dry mouth. The effect of the product will be compared to a control spray (water).

NCT ID: NCT03649789 Completed - Clinical trials for Periodontal Diseases

Periodontal Outcomes After Sanative Therapy

Start date: August 1, 2018
Phase:
Study type: Observational

Salivary gland hypofunction, or dry mouth, is a damaging oral condition that affects salivary gland production. Absence of saliva causes bad breath, dental decay, increased plaque accumulation, dry lips, mouth sores, and the inability to retain dentures or removable protheses. This study will determine if patients with dry mouth have different periodontal health than patients without dry mouth. Additionally, this study will examine if patients who have their periodontal maintenance appointments solely at a periodontal speciality clinic have different periodontal health than patients who alternate their appointments between a specialty office and their general dental office.

NCT ID: NCT03295019 Recruiting - Sleep Apnea Clinical Trials

"Hyaluronan" Formulation for Dry Mouth in Sleep Apnea Patients

Start date: August 4, 2017
Phase: N/A
Study type: Interventional

During routine clinical practice, it is observed that patients with suspected obstructive sleep apnea (OSA) often reported waking up with a dry mouth during the night or in the morning. This 9 week, cross-over group, randomized, single center, study will evaluate the efficacy of a proprietary formulation in comforting dry mouth in Sleep Apnea patients.

NCT ID: NCT03281486 Completed - Xerostomia Clinical Trials

"Hyaluronan" Formulation for Type 2 Diabetic Patients With Dry Mouth

Start date: January 28, 2018
Phase: N/A
Study type: Interventional

An increased incidence of dental caries in association with poorly controlled diabetes has also been reported, Xerostomia (dry mouth) has been reported to be a common complaint of patients with diabetes, Without adequate saliva production, both hard and soft tissues of the mouth can be severely damaged and become more susceptible to infections. This 9 week, cross-over group, randomized, single center, study will evaluate the efficacy of HA formulation in alleviating dry mouth in type 2 diabetic patients.

NCT ID: NCT03215251 Completed - Dry Mouth Clinical Trials

Effectiveness of an Intervention Bundle on Thirst Intensity and Dry Mouth Among Patients in ICUs

Start date: November 2015
Phase: N/A
Study type: Interventional

The study evaluates the effectiveness of an Intervention Bundle on Thirst Intensity and Dry Mouth among Patients admitted in ICUs. Patients were randomized into two groups - Experimental and Control group. Experimental group received intervention Bundle whereas control group didn't receive any intervention. Usual care was continued in both the groups.

NCT ID: NCT03035825 Completed - Dry Mouth Clinical Trials

Efficacy of Oral Moisturizing Jelly on Oral Health and Nutrition in Post-radiotherapy Head and Neck Cancer Patients

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

This randomized control trial aims to investigate the efficacy of oral moisturizing jelly in head and neck cancer patients with xerostomia.