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Study of OT202 in Treating Moderate to Severe Dry Eye

Dry Eye Clinical Trial

Official title:
A Phase II, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of OT202 Eye Drops in the Treatment of Moderate to Severe Dry Eye

Clinical Trial Summary

This is a phase II study to explore the optimal dosage of OT202 in treating dry eye.

Clinical Trial Description

Subjects successfully enrolled will enter a 2-week induction period of OT202 solvent eye drops, treated with OT202 three times daily (morning, afternoon, and evening), with 1-2 drops each time. On the day of the baseline visit (Visit 2), subjects will be assessed again to meet the inclusion and exclusion criteria. Subjects remain in the study are then randomized with a 1:1:1 ratio to 3 groups, the 0.5% OT202 eye drop group, 1% OT202 eye drop group, or OT202 solvent eye drop group, for an 8-week treatment period. Safety visits will be conducted 2 weeks after completion of the respective treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06435182
Study type Interventional
Source Ocumension Therapeutics (Shanghai) Co., Ltd
Contact
Status Completed
Phase Phase 2
Start date April 10, 2023
Completion date January 26, 2024
View Details
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