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Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye — IIR  

Dry Eye Clinical Trial

Official title:
Role of Neurotrophic Keratitis Versus Severity of Tear Film and Ocular Surface Parameters in Determining the Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye

Clinical Trial Summary

In this study the investigators plan to enroll three groups of patients: non-Sjogren's dry eye, Sjogren's dry eye and controls. The study has the following primary goals: 1. To determine whether dry eye is associated with reduced corneal sensation 2. To determine whether reduced corneal sensation is due to the severity of the dry eye, the type of dry eye (primarily aqueous deficient versus primarily evaporative) or entirely related to the presence of Sjogren's 3. To determine whether corneal sensation is associated with ocular or systemic pain symptoms Additionally, the study aims to compare the novel corneal esthesiometer measurements to confocal biomicroscopy findings in determining neurotrophic keratitis (NK) and assess correlations between corneal sensation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06364657
Study type Observational
Source Johns Hopkins University
Contact Richard C Medina, BA
Phone 626-343-3967
Email rmedin19@jh.edu
Status Not yet recruiting
Phase
Start date July 1, 2024
Completion date July 31, 2027
View Details
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