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Effects of Topical Insulin on Levels of Tear Inflammatory Mediators

Dry Eye Clinical Trial

Official title:
Effects of Topical Insulin on Levels of Tear Inflammatory Mediators Compared to Standard Artificial Tears and Normal Saline in Diabetics With Dry Eye Disease

Clinical Trial Summary

60 samples are take to determine the effects of topical insulin on tear inflammatory mediators interleukin 1a, interleukin 6 and matrix metalloprotenase 9 in diabetics with dry eye disease.

Clinical Trial Description

Tear samples are taken to compare the levels of inflammatory markers (IL 1a, IL6 and MMP 9) pre-and post treatment with topical insulin in normal saline compared to standard therapy and normal saline in diabetics with dry eyes and also to correlate the IL 1a, IL6 and MMP 9 levels with clinical outcomes in diabetics with dry eyes treated with topical insulin in normal saline, standard therapy and normal saline ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04877210
Study type Interventional
Source Universiti Kebangsaan Malaysia Medical Centre
Contact Atikah bt Asini, M.D.
Phone +60178254335
Email atikahasini@yahoo.com
Status Recruiting
Phase Phase 1
Start date October 22, 2020
Completion date January 26, 2022
View Details
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