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The Chronology of Lifitegrast Effect on Anterior Surface Rehabilitation (CLEAR) Study — CLEAR  

Dry Eye Clinical Trial

Official title:
The Chronology of Lifitegrast Effect on Anterior Surface Rehabilitation (CLEAR) Study: An Investigation on Lifitegrast's Speed of Onset in Improving Ocular Surface Health in Dry Eye Patients

Clinical Trial Summary

In patients with dry eye, defined as corneal staining and a reduced tear breakup time, lifitegrast will improve higher order aberrations, ocular scatter index, corneal staining, and TBUT as soon as 1 week after initiating treatment.

Clinical Trial Description

This is a multicenter, prospective, open label, self-controlled, single group study of the efficacy of Lifitegrast 5% in improving higher order aberrations, ocular scatter index, and best corrected visual acuity in patients with dry eye. All patients will receive lifitegrast 5% for 4 weeks and will be evaluated at baseline (before treatment) and at 7, 14, and 28 days ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04669561
Study type Interventional
Source Research Insight LLC
Contact
Status Completed
Phase Phase 4
Start date March 17, 2021
Completion date October 8, 2021
View Details
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