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Can Pregabalin Reduce the Frequency and Severity of Dry Eye Symptoms After Laser-assisted in Situ Keratomileusis?

Dry Eye Clinical Trial

Official title:
Can Pregabalin Reduce the Frequency and Severity of Dry Eye Symptoms After Laser-assisted in Situ Keratomileusis?

Clinical Trial Summary

Can Lyrica (Pregabalin) help prevent severe Dry Eye post LASIK surgery?

Clinical Trial Description

Dry eye symptoms can occur after LASIK surgery. They generally get better with time but in some patients, they can persist. The investigators believe that in some individuals, dry eye symptoms after LASIK persist because the nerves in the cornea become hypersensitive. The investigators wish to study if a medication, called pregabalin, can protect corneal nerves at the time of LASIK surgery and decrease the frequency and severity of dry eye symptoms 6 months after surgery. This medication has been used in a similar way to reduce the frequency of uncomfortable sensations after other surgeries (knee, abdomen) but has never been studied in LASIK surgery. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02701764
Study type Interventional
Source University of Miami
Contact
Status Completed
Phase Phase 2/Phase 3
Start date July 26, 2016
Completion date December 1, 2018
View Details
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