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Dry Eye clinical trials

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NCT ID: NCT05011708 Completed - Dry Eye Clinical Trials

I-DROP MGD Symptomatic Relief and Tear Film Stability

Start date: August 23, 2021
Phase: N/A
Study type: Interventional

The objective of the study is to compare the difference in tear film stability and symptomatic relief between I-DROP MGD and another commercially available drop in the Canadian market.

NCT ID: NCT04971031 Completed - Dry Eye Clinical Trials

A Clinical Trial to Assess Subjects With Dry Eye Disease.

Start date: June 15, 2021
Phase: Phase 2
Study type: Interventional

A Multi-Center Randomized, Double-Masked, Parallel Design, Vehicle-Controlled Phase 2 Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease

NCT ID: NCT04960696 Completed - Dry Eye Clinical Trials

Effect on Ocular Surface Symptoms of Online Education

Start date: April 14, 2021
Phase:
Study type: Observational [Patient Registry]

retrospective, observational study.

NCT ID: NCT04949295 Completed - Dry Eye Clinical Trials

Evaluation of Ocular Surface in Hemodialysis Patients by Ocular Surface Analyzer

Start date: January 1, 2021
Phase:
Study type: Observational

We clinically observed that some hemodialysis patients had corneal epithelial dryness, shedding, edema, and persistent epithelial nonunion after ocular surgery, which seriously affected the effect of surgery, and it is necessary to study the ocular surface characteristics of hemodialysis patients. In this study, we examined the ocular surface and analyzed and investigated the characteristics of the ocular surface in hemodialysis patients to provide a basis for ocular surface intervention or treatment in hemodialysis patients before ocular surgery in clinical practice.

NCT ID: NCT04911361 Completed - Dry Eye Clinical Trials

The DEPOT Study (Dry Eye Prescription Options for Therapy)

Start date: August 10, 2021
Phase: Phase 4
Study type: Interventional

Assessing DEXTENZA efficacy and safety when placed within the lower eyelid canaliculus for dry eye flares in comparison to topical loteprednol suspension.

NCT ID: NCT04899518 Completed - Dry Eye Clinical Trials

ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease

OASIS-1
Start date: May 19, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Study Evaluating the Safety and Efficacy of Two Concentrations (0.4% and 1%) of ALY688 Ophthalmic Solution in Subjects with Dry Eye Disease

NCT ID: NCT04889950 Completed - Dry Eye Clinical Trials

Clinical Study to Evaluate the Safety and Effectiveness of The Tixel Fractional System in the Treatment of Meibomian Gland Disfunction

Start date: October 26, 2021
Phase: N/A
Study type: Interventional

A Randomized, Masked (Evaluator), Controlled, Prospective Pilot Study of the Effectiveness and Safety of the Tixel®, Versus LipiFlow® in the Treatment of Meibomian Gland Dysfunction. Up to 30 patients (60 eyes) to be randomized in up to 2 clinical sites in Israel and/or Europe. study subject will receive three (3) treatments with Tixel in a monthly interval, and a single treatment for the control group. Follow-up will occur 1 month and 3 months following the last treatment.

NCT ID: NCT04837807 Completed - Dry Eye Clinical Trials

Digital Device Users Who Are Treated With Systane Hydration PF

Start date: August 18, 2021
Phase: Phase 4
Study type: Interventional

Systane Hydration PF is a recently released preservative-free artificial tear that is able to supplement the ocular surface's moisture while simultaneously soothing the eye. While Systane Hydration PF should in theory improve the symptoms and subsequently the quality of life of patients who have DES, this clinical application has yet to be tested. This drop furthermore is available in both unit-dose and multi-dose options; however, it is unclear if patient perceive a difference between the two dispensing methods. Therefore, the primary purpose of this study is to recruit patients who have DES and to treat them with Systane Hydration PF and determine how regular use of this drop impacts a patient's ocular surface symptoms and overall quality of life. This study will secondarily compare the two dispensing methods to determine if patients prefer one method over the other.

NCT ID: NCT04835623 Completed - Dry Eye Clinical Trials

CEQUA for Sjogren's Syndrome Dry Eye

Start date: June 21, 2021
Phase: Phase 4
Study type: Interventional

The primary objective of this study is to show that CEQUA (cyclosporine 0.09% ophthalmic solution) improves symptoms of dry eye disease in a population of patients with Sjogren's Syndrome diagnosis.

NCT ID: NCT04830956 Completed - Dry Eye Clinical Trials

Evaluation of Comfort in Subjects With Moderate Dry Eye Disease

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the comfort of an ocular lubricant in dry eye subjects. This study will be conducted in Canada and Australia.