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Dry Eye clinical trials

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NCT ID: NCT05945069 Recruiting - Dry Eye Clinical Trials

Feasibility of Dynamic Muscle Stimulation + Radiofrequency for Improving Blink Quality in Subjects With Dry Eye Disease

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

To demonstrate that DMSt + RF improves eye blink quality in subjects with dry eye disease

NCT ID: NCT05932238 Recruiting - Dry Eye Clinical Trials

Systane® Hydration PF and Systane® Hydration Preserved

Start date: October 6, 2023
Phase: N/A
Study type: Interventional

The purpose of this post-market clinical follow-up (PMCF) study is to assess the performance and safety of Systane Hydration Preservative Free (PF) in subjects experiencing dry eye symptoms (Group 1) and in contact lens (CL) wearers experiencing discomfort due to CL-related dryness (Group 2) and also Systane Hydration Preserved in CL wearers experiencing discomfort due to CL-related dryness (Group 3). Statistical analyses will be presented by group.

NCT ID: NCT05906381 Recruiting - Dry Eye Clinical Trials

Dry Eye Symptom Mitigation by Oral Intake of Probiotics

Start date: May 13, 2023
Phase: N/A
Study type: Interventional

This study investigates whether the oral intake of a probiotics capsule product may relieve dry eye symptoms. Participants will be aged between 20 - 65 years of age, with confirmed diagnosis of dry eye status. The participants will be assessed for several parameters and asked to take 1 probiotics capsule per day for 35 days. The parameters will include ocular surface health, tear volume, tear quality, intraocular pressure, tear osmolarity and serum biochemical test. After the 35 days are completed, the participants will be assessed again for the same parameters.

NCT ID: NCT05902364 Recruiting - Dry Eye Clinical Trials

Systane® Ultra Preservative Free Lubricant Eye Drops

Start date: October 28, 2023
Phase: N/A
Study type: Interventional

The purpose of this post-market clinical follow-up (PMCF) study is to assess the performance and safety of Systane Ultra Preservative-Free (PF) in subjects experiencing dry eye symptoms (Group 1) and contact lens (CL) wearers experiencing discomfort due to CL-related dryness (Group 2). Statistical analyses will be presented by group. This study will be conducted in Canada, Australia, and New Zealand.

NCT ID: NCT05895500 Recruiting - Dry Eye Clinical Trials

Evaluate the Safety and Efficacy of Calcitonin Gene-Related Peptide (CGRP) Antagonists in Patients With Dry Eye Disease and Asthenopia

Start date: May 10, 2023
Phase:
Study type: Observational [Patient Registry]

Safety and Efficacy of Medications for Migraine in Patients with Dry Eye Disease or Asthenopia

NCT ID: NCT05887336 Recruiting - Dry Eye Clinical Trials

Intra-Nasal Mechanical Stimulation (INMEST) as a Treatment Method for the Relief of Symptoms of Dry Eye

Start date: June 2023
Phase: N/A
Study type: Interventional

The purpose of the study is to investigate the degree of symptom relief in people with signs or symptoms of dry eyes after self-treatment at home with the Walther System delivering INMEST (intranasal mechanical stimulation). A total of 110 subjects are planned to be enrolled and randomized to either use an active device or a sham device. Both groups will also receive standard treatment in mainstream healthcare for symptoms of dry eye. The subject self-administer treatments at home, three times a week for six weeks, with a follow-up period of three months after end of treatment.

NCT ID: NCT05803798 Recruiting - Dry Eye Clinical Trials

Combined Treatment With Pulsed Light and Photobiomodulation Before Laser Refractive Surgery

TEBELID
Start date: June 6, 2023
Phase: N/A
Study type: Interventional

Ametropia is the first cause of reversible visual trouble. Recently, laser refractive surgery has increased in popularity. Unfortunately, dry eye is a common side effect, representing about 25% of patients after LASIK and 20% after SMILE. Even if symptoms are usually released by artificial tears, there can be very uncomfortable for patients, decrease productivity and quality of life and be the source of unsatisfaction after surgery. The goal of our study is to study the efficiency of a preventive associated treatment by intense-pulsed-light and low-level-light therapy with EYE-LIGHT® device before laser refractive surgery. Recent study confirmed the efficacity of this treatment in meibomian glund dysfunction, the predominant dry eye mecanism.

NCT ID: NCT05754437 Recruiting - Dry Eye Clinical Trials

Efficacy of Low-Level Light Therapy in Reducing Dry Eye in Patients Undergoing Cataract Surgery

Start date: March 30, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the effectiveness of Low Level Light Therapy (LLLT) in reducing the incidence or alleviating the severity of DED due to meibomian gland dysfunction in otherwise healthy patients undergoing cataract surgery. Participants will be randomly assigned in a 1:1 ratio to either a treatment group or a control group. The treatment group will receive LLLT one week before and one week after cataract surgery; the control group will not recieve LLLT at any time. Researchers will compare the treatment and the control group to see if patients receiving LLLT present with reduced signs and symptoms of ocular surface dysfunction with respect to the control group.

NCT ID: NCT05748951 Recruiting - Dry Eye Clinical Trials

Evaluating a Device for Blocking the Tear Duct

Start date: March 7, 2023
Phase: N/A
Study type: Interventional

Participants will receive a tear duct plug to see if their eye comfort improves.

NCT ID: NCT05737108 Recruiting - Dry Eye Clinical Trials

Bilberry-containing Capsules for Dry Eye Mitigation

Start date: August 24, 2022
Phase: N/A
Study type: Interventional

This study investigates whether the oral intake of a bilberry capsule product may relieve dry eye symptoms. Participants will be aged between 20 - 65 years of age, with confirmed diagnosis of dry eye status. The participants will be assessed for several parameters and asked to take 4 bilberry capsules per day for 30 days. The parameters will include ocular surface health, tear volume, tear quality, intraocular pressure, and tear compositions. After the 30 days are completed, the participants will be assessed again for the same parameters.