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Clinical Trial Summary

study the effect of different concentrations of benzalkonium chloride on the ocular surface of non-dry-eyed patients post cataract surgery.


Clinical Trial Description

60 eyes of will be included in this study. - 20 eyes will receive regular Tobradex 0.1mg/ml BAK 5 times per day (Group 1). - 20 eyes will receive Dexathalm multidose 0.05mg/ml BAK 5 times per day (Group 2). - 20 eyes will receive single dose unit Dexathalm NO BAK 5 times per day (Group 3). Preoperative assessment: All selected patients will receive thorough explanation of the study design and aims, an informed consent will be obtained from all patients. Tear break up time (TBUT) will be measured non-invasively by Ocular Surface analyzer. Ocular Surface disease index will be calculated by filling a questionnaire. 12-item questionnaire provide a rapid assessment of the symptoms of ocular irritation consistent with dry eye disease and their impact on vision-related functioning. Postoperative: 1. All patients will be examined at day1, 1 week and 3 week postoperative. 2. At 3 weeks re-evaluate I. TBUT by non-invasive ocular surface analyzer II. OSDI by filling the questionnaire. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06404541
Study type Interventional
Source Kasr El Aini Hospital
Contact
Status Active, not recruiting
Phase Phase 4
Start date January 10, 2024
Completion date May 2024

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