Diurnal Variation in Tear Osmolarity

Status Completed

Clinical Trial Summary

The purpose of this study is to measure the change in Tear Osmolarity during the course of the day to support clinical diagnosis of aqueous deficiency or meibomian gland disease and differentiate between the two forms of dry eye.

Clinical Trial Description

The premise of this study is that dry eye disease, specifically tear osmolarity, changes during the course of the day based on the etiology of the dry eye and that aqueous-deficiency dry eye will worsen during the course of the day while meibomian gland deficiency will stabilize or possibly even improve during the course of the day. ;

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01321424
Study type	Observational
Source	Ophthalmic Consultants of Long Island
Contact
Status	Completed
Phase	N/A
Start date	March 2011
Completion date	March 2016

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