Dry Eye Disease Clinical Trial
Official title:
The Evaluation of Thiol Redox Status in Conjunctiva of Dry Eye Patients
Dry eye disease is related with oxidative stress at the ocular surface. GSH is one of the key factor of protect from oxidative stress. To evaluate thiol status of ocular surface cells by monitoring GSH concentration, we can evaluate the severity of dry eye.
Status | Not yet recruiting |
Enrollment | 50 |
Est. completion date | March 2010 |
Est. primary completion date | December 2008 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | 20 Years and older |
Eligibility |
Inclusion Criteria: - dry eye patients - control volunteers Exclusion Criteria: - Young (less than 20) patients - The patients who rejected this study |
Observational Model: Case Control
Country | Name | City | State |
---|---|---|---|
Japan | Kyoto Prefectural University of Medicine hospital | Kyoto |
Lead Sponsor | Collaborator |
---|---|
Meiji University of Oriental Medicine | Kyoto Prefectural University of Medicine |
Japan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Tear amount, tear break up time, and so on are measured clinically. The thiol redox status is measured by staining the membrane. | Once a month (totally 2-4 times) at the clinic | Yes |
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