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Dry Eye Disease clinical trials

View clinical trials related to Dry Eye Disease.

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NCT ID: NCT05759208 Completed - Dry Eye Disease Clinical Trials

The Study Evaluating the Efficacy and Safety of OK-101 in Subjects With Dry Eye Disease

Start date: April 28, 2023
Phase: Phase 2
Study type: Interventional

The objective of this study is to compare the safety and efficacy of OK-101 Ophthalmic Solution to placebo for the treatment of the signs and symptoms of dry eye.

NCT ID: NCT05758753 Enrolling by invitation - Dry Eye Disease Clinical Trials

QST for Corneal Nerve Function

Start date: May 16, 2023
Phase: N/A
Study type: Interventional

This study is designed to learn more about the impact different types of stimuli, such as heat, cold and vibration, can have on ocular pain response. This is called quantitative sensory testing (QST). Most procedures being performed in this study, except the QST, are standard of care which means they are performed during the participant's routine eye examination.

NCT ID: NCT05745064 Completed - Dry Eye Disease Clinical Trials

A Study of TL-925 as a Treatment for Dry Eye Disease

Start date: February 27, 2023
Phase: Phase 2
Study type: Interventional

In this prospective, Phase 2, multicenter, randomized, double-masked, placebo-controlled, parallel-arm study, approximately 100 subjects with moderate to severe dry eye disease (DED) will be randomly assigned (1:1) to receive either TL-925 or placebo as topical ophthalmic eye drops administered bilaterally BID. The study will comprise two phases: 2-weeks screening/run-in and 4-weeks double-masked treatment.

NCT ID: NCT05743764 Completed - Dry Eye Disease Clinical Trials

HU007 in Patients With Dry Eye Syndrome

Start date: March 23, 2023
Phase: Phase 3
Study type: Interventional

A multicenter, Randomized, Double blind, Restasis®-controlled Non-inferiority, Moisview® Eye Drops Controlled Superiority, Phase III Study to Evaluate the Efficacy and Safety of HU007 Eye Drops in Patients with Dry Eye Syndrome

NCT ID: NCT05738629 Not yet recruiting - Dry Eye Disease Clinical Trials

Safety and Efficacy of Pluripotent Stem Cell-derived Mesenchymal Stem Cell Exosome (PSC-MSC-Exo) Eye Drops Treatment for Dry Eye Diseases Post Refractive Surgery and Associated With Blepharospasm

Start date: March 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the preliminary safety and effectiveness of Pluripotent Stem Cell-derived Mesenchymal Stem Cell Exosome (PSC-MSC-Exo) Eye Drops in the treatment of dry eye diseases post refractive surgery and associated with blepharospasm

NCT ID: NCT05724056 Not yet recruiting - Dry Eye Disease Clinical Trials

Idroflog® for Treatment of Dry Eye Disease (IDROFLOG)

IDROFLOG
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

This study aims at demonstrating the non-inferiority of Idroflog compared to sodium hyaluronate 0.18% for the disease improvement of people with documented history of dry eyes and use of tear substitutes for at least 3 months.

NCT ID: NCT05695781 Recruiting - Dry Eye Disease Clinical Trials

Assessment of the Safety and Efficacy of BRM421 Ophthalmic Solutions in Dry Eye Subjects.

Start date: February 27, 2023
Phase: Phase 3
Study type: Interventional

The objective of this study is to compare the safety and efficacy of BRM421 OS to vehicle for the treatment of the signs and symptoms of dry eye disease.

NCT ID: NCT05660681 Completed - Dry Eye Disease Clinical Trials

Evaluation of the Tolerability and Efficacy of CWT-f-002 Lubricant Eye Drops

Start date: December 12, 2022
Phase: N/A
Study type: Interventional

The primary objective is to evaluate the tolerability and efficacy of CWT-f-002 lubricant eye drops in the treatment of the signs and symptoms of dry eye disease.

NCT ID: NCT05629364 Terminated - Dry Eye Disease Clinical Trials

A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, Versus Vehicle Control in the Treatment of Dry Eye Disease in Patients With Autoimmune Disease

Start date: March 15, 2023
Phase: Phase 2
Study type: Interventional

A Multi-Centre, Randomised, Controlled, Masked Phase 2 Study of the Safety and Efficacy of KIO-101 Ophthalmic Solution, versus Vehicle Control in the treatment of Dry Eye Disease in Patients with Autoimmune Disease

NCT ID: NCT05604651 Completed - Dry Eye Disease Clinical Trials

Comparison of Mucin Levels at the Ocular Surface of Visual Display Users With and Without Dry Eye Disease

Start date: March 1, 2021
Phase:
Study type: Observational

The study aimed to evaluate 1) if levels of the glycocalyx membrane mucins, including MUC1, MUC4, MUC16 and MUC20, are altered in conjunctival cells of visual display users With and Without Dry Eye Disease, and 2) if mucin levels correlate with dry eye clinical diagnostic data.