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Dry Eye Disease clinical trials

View clinical trials related to Dry Eye Disease.

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NCT ID: NCT05411367 Completed - Dry Eye Disease Clinical Trials

A Study for Evaluation of the Efficacy and Safety of SI-614 Ophthalmic Solution in Patient With Dry Eye

SIDE
Start date: July 28, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of SI-614 ophthalmic solution compared with placebo in patients with dry eye

NCT ID: NCT05403827 Completed - Dry Eye Disease Clinical Trials

A Study to Confirm the Efficacy and Safety of K-161 Ophthalmic Solution for Treatment of Moderate to Severe Dry Eye Disease

Start date: July 3, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of K-161 ophthalmic solution for the treatment of moderate to severe dry eye disease.

NCT ID: NCT05378945 Completed - Dry Eye Disease Clinical Trials

Clinical Trial to Evaluate the Efficacy and Safety of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease

Start date: July 22, 2022
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the safety and effectiveness of OC-01 (varenicline solution) Nasal Spray as compared to placebo (vehicle) on signs and symptoms of dry eye disease.

NCT ID: NCT05372107 Completed - Dry Eye Disease Clinical Trials

A Study of AG-80308 in Dry Eye Patients

Start date: June 13, 2022
Phase: Phase 1
Study type: Interventional

This is a multicenter, double-masked, randomized, parallel-group study with topical AG-80308 eye drops in dry eye patients.

NCT ID: NCT05370495 Completed - Dry Eye Disease Clinical Trials

Study of SY-201 Ophthalmic Solution in Subjects With Dry Eye Disease

Start date: July 25, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase 2, multi-center, double-masked, randomized, vehicle-controlled, dose-response, parallel-group study designed to evaluate the safety and tolerability and ocular efficacy of SY-201 Ophthalmic Solution versus vehicle over a 60-day treatment period in subjects with dry eye disease (DED).

NCT ID: NCT05360966 Completed - Dry Eye Disease Clinical Trials

Study Evaluating the Safety and Efficacy of AR-15512 (COMET-3)

Start date: July 18, 2022
Phase: Phase 3
Study type: Interventional

This will be a Phase 3, multicenter, vehicle-controlled, double-masked, randomized study conducted at approximately 20 sites in the United States. All subjects enrolled will have dry eye disease (DED). The study will consist of Screening (Day -14) and Baseline (Day 1) visits as well as visits at Day 7, Day 14, Day 28, and Day 90 (Study Exit).

NCT ID: NCT05310422 Completed - Dry Eye Disease Clinical Trials

Safety Study of Tivanisiran to Treat Dry Eye

FYDES
Start date: March 24, 2022
Phase: Phase 3
Study type: Interventional

This study will examine the safety of tivanisiran sodium eye drops versus vehicle when dosed once daily for 1 year in subjects with signs and symptoms of dry eye disease (DED).

NCT ID: NCT05285644 Completed - Dry Eye Disease Clinical Trials

Study Evaluating the Safety and Efficacy of AR-15512

COMET-2
Start date: May 9, 2022
Phase: Phase 3
Study type: Interventional

This will be a Phase 3, multicenter, vehicle-controlled, double-masked, randomized study conducted at approximately 20 sites in the United States. All subjects enrolled will have dry eye disease (DED). The study will consist of Screening (Day -14) and Baseline (Day 1) visits as well as visits at Day 7, Day 14, Day 28, and Day 90 (Study Exit).

NCT ID: NCT05271422 Completed - Dry Eye Disease Clinical Trials

Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Scheduled for LASEK Surgery

Start date: February 28, 2020
Phase: N/A
Study type: Interventional

This study aims to evaluate the efficacy and safety of applying pulse electrical stimulation around eye in dry eye disease patients who are scheduled for LASEK surgery.

NCT ID: NCT05241470 Completed - Dry Eye Disease Clinical Trials

Study of ST-100 as Treatment for Dry Eye Disease

Start date: May 17, 2021
Phase: Phase 2
Study type: Interventional

The objective of this study is to compare the safety and efficacy of two different concentrations of ST-100 Ophthalmic Solution to placebo (vehicle) for the treatment of the signs and symptoms of dry eye.